Genetics, Vol. 177, 1269-1276, November 2007, Copyright © 2007
doi:10.1534/genetics.107.074112

Drosophila Biology in the Genomic Age

Therese Ann Markow*,1 and Patrick M. O'Grady{dagger}

* Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona 85721 and {dagger} Division of Organisms and the Environment, University of California, Berkeley, California 94720

1 Corresponding author: Department of Ecology and Evolutionary Biology, BioSciences West 310, 1041 E. Lowell, P.O. Box 210088, Tucson, AZ 85721.
E-mail: tmarkow{at}arl.arizona.edu

Over the course of the past century, flies in the family Drosophilidae have been important models for understanding genetic, developmental, cellular, ecological, and evolutionary processes. Full genome sequences from a total of 12 species promise to extend this work by facilitating comparative studies of gene expression, of molecules such as proteins, of developmental mechanisms, and of ecological adaptation. Here we review basic biological and ecological information of the species whose genomes have recently been completely sequenced in the context of current research.




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