Originally published as Genetics Published Articles Ahead of Print on July 29, 2007.

Genetics, Vol. 177, 1233-1237, October 2007, Copyright © 2007
doi:10.1534/genetics.107.075283

Natural Variation of ebony Gene Controlling Thoracic Pigmentation in Drosophila melanogaster

* Division of Population Genetics, National Institute of Genetics, Mishima 411-8540, Japan, {dagger} Department of Genetics, Graduate University for Advanced Studies (Sokendai), Mishima 411-8540, Japan, {ddagger} Genetic Strains Research Center, National Institute of Genetics, Mishima, Shizuoka, Japan and § Department of Biosystems Science, Graduate University for Advanced Studies (Sokendai), Hayama 240-0193, Japan

1 Corresponding author: Division of Population Genetics, National Institute of Genetics, 1,111 Yata, Mishima 411-8540, Japan. Email: atakahas{at}lab.nig.ac.jp

We identified the causal genetic variation for the difference in the thoracic trident pigmentation intensity between two wild-derived strains of Drosophila melanogaster. It was found to be the difference in expression level of ebony, which codes for an enzyme in the melanin-synthesis pathway and has pleiotropic effects on vision and behavior.