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Originally published as Genetics Published Articles Ahead of Print on August 24, 2007.
Genetics, Vol. 177, 669-672, September 2007, Copyright © 2007
doi:10.1534/genetics.107.074302
Genetic Dissection of Cytonuclear Epistasis in Line Crosses
Zaixiang Tang, Xuefeng Wang, Zhiqiu Hu, Zefeng Yang and Chenwu Xu1
Jiangsu Provincial Key Laboratory of Crop Genetics and Physiology, Key Laboratory of Plant Functional Genomics of Ministry of Education, Yangzhou University, Yangzhou 225009, China
1 Corresponding author: Department of Plant Genetics and Breeding, Yangzhou University, Yangzhou 225009, China.
E-mail: qtls{at}yzu.edu.cn
Dissection of cytonuclear interactions is fundamentally important for understanding the genetic architecture of complex traits. Here we propose a mating design based on reciprocal crosses and extend the existing QTL mapping method to evaluate the contribution of cytoplasm and QTL x cytoplasm interactions to the phenotypic variation. Efficiency of the design and method is demonstrated via simulated data.
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