- THIS ARTICLE
- Full Text
- Full Text (PDF)
- Data Supplement
-
All Versions of this Article:
genetics.106.067314v1
176/1/343 most recent - Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Email this article to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Chang, A. S.
- Articles by Noor, M. A. F.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Chang, A. S.
- Articles by Noor, M. A. F.
Originally published as Genetics Published Articles Ahead of Print on February 4, 2007.
Genetics, Vol. 176, 343-349, May 2007, Copyright © 2007
doi:10.1534/genetics.106.067314
The Genetics of Hybrid Male Sterility Between the Allopatric Species Pair Drosophila persimilis and D. pseudoobscura bogotana: Dominant Sterility Alleles in Collinear Autosomal Regions
Audrey S. Chang1 and Mohamed A. F. Noor
Department of Biology, Duke University, Durham, North Carolina 27708
1 Corresponding author: Department of Biology, Box 90338, Duke University, Durham, NC 27708.
E-mail: audrey.chang{at}duke.edu
F1 hybrid male sterility is thought to result from interactions between loci on the X chromosome and dominant-acting loci on the autosomes. While X-linked loci that contribute to hybrid male sterility have been precisely localized in many animal taxa, their dominant autosomal interactors have been more difficult to localize precisely and/or have been shown to be of relatively smaller effect. Here, we identified and mapped at least four dominant autosomal factors contributing to hybrid male sterility in the allopatric species pair Drosophila persimilis and D. pseudoobscura bogotana. Using these results, we tested predictions of reduced recombination models of speciation. Consistent with these models, three of the four QTL associated with hybrid male sterility occur in collinear (uninverted) regions of these genomes. Furthermore, these QTL do not contribute significantly to hybrid male sterility in crosses between the sympatric species D. persimilis and D. pseudoobscura pseudoobscura. The autosomal loci identified in this study provide the basis for introgression mapping and, ultimately, for molecular cloning of interacting genes that contribute to F1 hybrid sterility.
This article has been cited by other articles:
 |
|
 |
|
  L. C. Moyle and T. Nakazato Comparative Genetics of Hybrid Incompatibility: Sterility in Two Solanum Species Crosses Genetics, July 1, 2008; 179(3): 1437 - 1453. [Abstract] [Full Text] [PDF]
|
|