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Originally published as Genetics Published Articles Ahead of Print on September 15, 2006.
Genetics, Vol. 174, 1685-1688, November 2006, Copyright © 2006
doi:10.1534/genetics.106.062893
The Aspergillus nidulans rcoA Gene Is Required for veA-Dependent Sexual Development
Richard B. Todd1, Michael J. Hynes and Alex Andrianopoulos
Department of Genetics, University of Melbourne, Parkville, Victoria 3010, Australia
1 Corresponding author: Department of Genetics, University of Melbourne, Parkville, Victoria 3010, Australia.
E-mail: rbtodd{at}unimelb.edu.au
The Aspergillus nidulans rcoA
mutant exhibits growth and developmental defects. We show that the rcoA
mutant lacks cleistothecia and is self-sterile. In crosses with wild-type strains, rcoA
nuclei do not contribute to the cleistothecial walls. Furthermore, sexual development resulting from veA overexpression is rcoA dependent, indicating that rcoA lies downstream of veA in the sexual development pathway.