help button home button Genetics J Neurophys
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Originally published as Genetics Published Articles Ahead of Print on September 1, 2006.

Genetics, Vol. 174, 1421-1430, November 2006, Copyright © 2006
doi:10.1534/genetics.106.062588

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Data Supplement
Right arrow All Versions of this Article:
genetics.106.062588v1
174/3/1421    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wright, S. I.
Right arrow Articles by Charlesworth, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wright, S. I.
Right arrow Articles by Charlesworth, D.

Testing for Effects of Recombination Rate on Nucleotide Diversity in Natural Populations of Arabidopsis lyrata

Stephen I. Wright*,1, John Paul Foxe*, Leah DeRose-Wilson{dagger}, Akira Kawabe{ddagger}, Mark Looseley{ddagger},2, Brandon S. Gaut{dagger} and Deborah Charlesworth{ddagger}

* Department of Biology, York University, Toronto, Ontario M3J 1P3, Canada, {dagger} Department of Ecology and Evolutionary Biology, University of California, Irvine, California 92697 and {ddagger} Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, United Kingdom

1 Corresponding author: Department of Biology, York University, 4700 Keele St., Toronto, ON M3J 1P3, Canada. 
E-mail: stephenw{at}yorku.ca

We investigated DNA sequence diversity for loci on chromosomes 1 and 2 in six natural populations of Arabidopsis lyrata and tested for the role of natural selection in structuring genomewide patterns of variability, specifically examining the effects of recombination rate on levels of silent polymorphism. In contrast with theoretical predictions from models of genetic hitchhiking, maximum-likelihood-based analyses of diversity and divergence do not suggest reduction of diversity in the region of suppressed recombination near the centromere of chromosome 1, except in a single population from Russia, in which the pericentromeric region may have undergone a local selective sweep or demographic process that reduced variability. We discuss various possibilities that might explain why nucleotide diversity in most A. lyrata populations is not related to recombination rate, including genic recombination hotspots, and low gene density in the low recombination rate region.




This article has been cited by other articles:


Home page
 Mol Biol EvolHome page
J. P. Foxe, V.-u.-N. Dar, H. Zheng, M. Nordborg, B. S. Gaut, and S. I. Wright
Selection on Amino Acid Substitutions in Arabidopsis
Mol. Biol. Evol., July 1, 2008; 25(7): 1375 - 1383.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
A. Kawabe, A. Forrest, S. I. Wright, and D. Charlesworth
High DNA Sequence Diversity in Pericentromeric Genes of the Plant Arabidopsis lyrata
Genetics, June 1, 2008; 179(2): 985 - 995.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
K. M. Hazzouri, A. Mohajer, S. I. Dejak, S. P. Otto, and S. I. Wright
Contrasting Patterns of Transposable-Element Insertion Polymorphism and Nucleotide Diversity in Autotetraploid and Allotetraploid Arabidopsis Species
Genetics, May 1, 2008; 179(1): 581 - 592.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
A. D. Cutter
Multilocus Patterns of Polymorphism and Selection Across the X Chromosome of Caenorhabditis remanei
Genetics, March 1, 2008; 178(3): 1661 - 1672.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
H. Kuittinen, A. Niittyvuopio, P. Rinne, and O. Savolainen
Natural Variation in Arabidopsis lyrata Vernalization Requirement Conferred by a FRIGIDA Indel Polymorphism
Mol. Biol. Evol., February 1, 2008; 25(2): 319 - 329.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
E. Kamau, B. Charlesworth, and D. Charlesworth
Linkage Disequilibrium and Recombination Rate Estimates in the Self-Incompatibility Region of Arabidopsis lyrata
Genetics, August 1, 2007; 176(4): 2357 - 2369.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
J. O. Borevitz, S. P. Hazen, T. P. Michael, G. P. Morris, I. R. Baxter, T. T. Hu, H. Chen, J. D. Werner, M. Nordborg, D. E. Salt, et al.
Genome-wide patterns of single-feature polymorphism in Arabidopsis thaliana
PNAS, July 17, 2007; 104(29): 12057 - 12062.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2006 by the Genetics Society of America.