- THIS ARTICLE
- Full Text
- Full Text (PDF)
-
All Versions of this Article:
genetics.106.060681v1
174/3/1397 most recent - Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Email this article to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Fearnhead, P.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Fearnhead, P.
Originally published as Genetics Published Articles Ahead of Print on September 1, 2006.
Genetics, Vol. 174, 1397-1406, November 2006, Copyright © 2006
doi:10.1534/genetics.106.060681
Perfect Simulation From Nonneutral Population Genetic Models: Variable Population Size and Population Subdivision
Paul Fearnhead1
Department of Mathematics and Statistics, Lancaster University, Lancaster, LA1 4YF, United Kingdom
1 Author e-mail: p.fearnhead{at}lancs.ac.uk
We show how the idea of monotone coupling from the past can produce simple algorithms for simulating samples at a nonneutral locus under a range of demographic models. We specifically consider a biallelic locus and either a general variable population size mode or a general migration model for population subdivision. We investigate the effect of demography on the efficacy of selection and the effect of selection on genetic divergence between populations.