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Genetics, Vol. 172, 2683-2688, April 2006, Copyright © 2006
doi:10.1534/genetics.105.051029
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Functions in Mitochondria

* Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, New York 14263 and
Johns Hopkins Oncology Center, Baltimore, Maryland 21231-1000
1 Corresponding author: Department of Cancer Genetics, Cell and Virus Bldg., Room 247, Roswell Park Cancer Institute, Elm and Carlton Sts., Buffalo, NY 14263.
E-mail: keshav.singh{at}roswellpark.org
and Rev1 proteins participate in the mitochondrial DNA mutagenesis. Supporting this evidence, both polymerase
and Rev1p were found to be localized in the mitochondria. This is the first report demonstrating that the DNA polymerase
and Rev1 proteins function in the mitochondria.
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