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Genetics, Vol. 172, 17-26, January 2006, Copyright © 2006
doi:10.1534/genetics.105.045922
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Department of Biological Sciences, State University of New York, Albany, New York 12222
1 Address for correspondence: Department of Biological Sciences, State University of New York, 1400 Washington Ave., Albany, NY 12222.
E-mail: ingnang{at}albany.edu
-phages that differ only in their lysis times was constructed. For each phage strain, the lysis time, burst size, and fitness (growth rate) were determined. The result showed that there is a positive linear relationship between lysis time and burst size. Moreover, the strain with an intermediate lysis time has the highest fitness, indicating the existence of an optimal lysis time. A mathematical model is also constructed to describe the population dynamics of phage infection. Computer simulations using parameter values derived from phage
-infection also showed an optimal lysis time. However, both the optimum and the fitness are different from the experimental result. The evolution of phage lysis timing is discussed from the perspectives of multiple infection and life-history trait evolution. This article has been cited by other articles:
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