help button home button Genetics AJP: Gastro and Liver
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Originally published as Genetics Published Articles Ahead of Print on October 16, 2004.

Genetics, Vol. 171, 557-570, October 2005, Copyright © 2005
doi:10.1534/genetics.104.034686

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Supplemental Data
Right arrow All Versions of this Article:
genetics.104.034686v1
171/2/557    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Jiggins, C. D.
Right arrow Articles by Bermingham, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jiggins, C. D.
Right arrow Articles by Bermingham, E.

A Genetic Linkage Map of the Mimetic Butterfly Heliconius melpomene

Chris D. Jiggins*,1, Jesus Mavarez{dagger},{ddagger}, Margarita Beltrán{dagger}, W. Owen McMillan§, J. Spencer Johnston** and Eldredge Bermingham{ddagger}

* Institute of Evolutionary Biology, University of Edinburgh, Edinburgh EH9 3JT, United Kingdom, {ddagger} Smithsonian Tropical Research Institute, AA2072 Balboa, República de Panamá, {dagger} The Galton Laboratory, Department of Biology, University College London, London NW1 2HE, United Kingdom, § Departamento de Biología, Universidad de Puerto Rico, San Juan, Puerto Rico 00931-3360 and ** Department of Entomology, Texas A&M University, College Station, Texas 77843

1 Corresponding author: Institute of Evolutionary Biology, Ashworth Laboratories, West Mains Rd., University of Edinburgh, Edinburgh EH9 3JT, United Kingdom.
E-mail: chris.jiggins{at}ed.ac.uk

Heliconius melpomene is a mimetic butterfly that exhibits great geographic variation in color pattern. We present here a genetic linkage map based on analysis of genetic markers in 73 individuals from a single F2 family, offspring of a cross between H. m. cythera from western Ecuador and H. m. melpomene from French Guiana. A novel "three-step method" is described for the analysis of dominant markers in an F2 cross, using outbred parental strains and taking advantage of the lack of crossing over in female Lepidoptera. This method is likely to prove useful for future mapping studies in outbred species with crossing over restricted to one sex, such as the Lepidoptera and Drosophila. The resulting linkage map has 21 linkage groups corresponding to the 21 chromosomes of H. melpomene and includes 219 AFLP markers, 23 microsatellites, 19 single-copy nuclear genes, and the color pattern switch genes Yb and Sb. The marker density is high, averaging >1/7 cM. The total map length is 1616 cM and the average chromosome length is 77 cM. The genome size of H. melpomene was estimated to be 292 Mb, giving a relationship of physical-to-map distance of 180 kb/cM. This map forms the basis for future comparative linkage analysis of color pattern evolution in Heliconius.




This article has been cited by other articles:


Home page
 GeneticsHome page
E. G. Pringle, S. W. Baxter, C. L. Webster, A. Papanicolaou, S. F. Lee, and C. D. Jiggins
Synteny and Chromosome Evolution in the Lepidoptera: Evidence From Mapping in Heliconius melpomene
Genetics, September 1, 2007; 177(1): 417 - 426.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
S. M. Rogers, N. Isabel, and L. Bernatchez
Linkage Maps of the dwarf and Normal Lake Whitefish (Coregonus clupeaformis) Species Complex and Their Hybrids Reveal the Genetic Architecture of Population Divergence
Genetics, January 1, 2007; 175(1): 375 - 398.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
M. R. Kronforst, D. D. Kapan, and L. E. Gilbert
Parallel Genetic Architecture of Parallel Adaptive Radiations in Mimetic Heliconius Butterflies
Genetics, September 1, 2006; 174(1): 535 - 539.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
Y. Yasukochi, L. A. Ashakumary, K. Baba, A. Yoshido, and K. Sahara
A Second-Generation Integrated Map of the Silkworm Reveals Synteny and Conserved Gene Order Between Lepidopteran Insects
Genetics, July 1, 2006; 173(3): 1319 - 1328.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
D. D. Kapan, N. S. Flanagan, A. Tobler, R. Papa, R. D. Reed, J. Acevedo Gonzalez, M. Ramirez Restrepo, L. Martinez, K. Maldonado, C. Ritschoff, et al.
Localization of Mullerian Mimicry Genes on a Dense Linkage Map of Heliconius erato
Genetics, June 1, 2006; 173(2): 735 - 757.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
M. R. Kronforst, L. G. Young, D. D. Kapan, C. McNeely, R. J. O'Neill, and L. E. Gilbert
Linkage of butterfly mate preference and wing color preference cue at the genomic location of wingless
PNAS, April 25, 2006; 103(17): 6575 - 6580.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
X.-X. Miao, S.-J. Xub, M.-H. Li, M.-W. Li, J.-H. Huang, F.-Y. Dai, S. W. Marino, D. R. Mills, P. Zeng, K. Mita, et al.
Simple sequence repeat-based consensus linkage map of Bombyx mori
PNAS, November 8, 2005; 102(45): 16303 - 16308.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2005 by the Genetics Society of America.