- THIS ARTICLE
- Full Text
- Full Text (PDF)
- Supplemental Data
-
All Versions of this Article:
genetics.105.042051v1
171/1/227 most recent - Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Email this article to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Kai, W.
- Articles by Suzuki, Y.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Kai, W.
- Articles by Suzuki, Y.
Originally published as Genetics Published Articles Ahead of Print on June 21, 2005.
Genetics, Vol. 171, 227-238, September 2005, Copyright © 2005
doi:10.1534/genetics.105.042051
A Genetic Linkage Map for the Tiger Pufferfish, Takifugu rubripes
Wataru Kai*,1,
Kiyoshi Kikuchi*,1,2,
Masashi Fujita*,
Hiroaki Suetake*,
Atushi Fujiwara
,
Yasutoshi Yoshiura,
Mitsuru Ototake,
Byrappa Venkatesh
,
Kadoo Miyaki
and
Yuzuru Suzuki*
* Fisheries Laboratory, The University of Tokyo, Maisaka, Shizuoka 431-0214, Japan, National Research Institute of Aquaculture, Fisheries Research Agency, Tamaki, Mie 519-0423, Japan, Institute of Molecular and Cell Biology, Singapore 138673, Republic of Singapore and Nagasaki Prefectural Institute of Fisheries, Taira, Nagasaki 851-2213, Japan
2 Corresponding author: Fisheries Laboratory, The University of Tokyo, 2971-4 Maisaka, Shizuoka 431-0214, Japan.
E-mail: akikuchi{at}mail.ecc.u-tokyo.ac.jp
The compact genome of the tiger pufferfish, Takifugu rubripes (fugu), has been sequenced to the "draft" level and annotated to identify all the genes. However, the assembly of the draft genome sequence is highly fragmented due to the lack of a genetic or a physical map. To determine the long-range linkage relationship of the sequences, we have constructed the first genetic linkage map for fugu. The maps for the male and female spanning 697.1 and 1213.5 cM, respectively, were arranged into 22 linkage groups by markers heterozygous in both parents. The resulting map consists of 200 microsatellite loci physically linked to genome sequences spanning 
39 Mb in total. Comparisons of the genome maps of fugu, other teleosts, and mammals suggest that syntenic relationship is more conserved in the teleost lineage than in the mammalian lineage. Map comparisons also show a pufferfish lineage-specific rearrangement of the genome resulting in colocalization of two Hox gene clusters in one linkage group. This map provides a foundation for development of a complete physical map, a basis for comparison of long-range linkage of genes with other vertebrates, and a resource for mapping loci responsible for phenotypic differences among Takifugu species.
This article has been cited by other articles:
 |
|
 |
|
  N. Tripathi, M. Hoffmann, E.-M. Willing, C. Lanz, D. Weigel, and C. Dreyer Genetic linkage map of the guppy, Poecilia reticulata, and quantitative trait loci analysis of male size and colour variation Proc R Soc B, June 22, 2009; 276(1665): 2195 - 2208. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Sugamata, H. Suetake, K. Kikuchi, and Y. Suzuki Teleost B7 Expressed on Monocytes Regulates T Cell Responses J. Immunol., June 1, 2009; 182(11): 6799 - 6806. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Yamanoue, M. Miya, K. Matsuura, S. Miyazawa, N. Tsukamoto, H. Doi, H. Takahashi, K. Mabuchi, M. Nishida, and H. Sakai Explosive Speciation of Takifugu: Another Use of Fugu as a Model System for Evolutionary Biology Mol. Biol. Evol., March 1, 2009; 26(3): 623 - 629. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Bouza, M. Hermida, B. G. Pardo, C. Fernandez, G. G. Fortes, J. Castro, L. Sanchez, P. Presa, M. Perez, A. Sanjuan, et al. A Microsatellite Genetic Map of the Turbot (Scophthalmus maximus) Genetics, December 1, 2007; 177(4): 2457 - 2467. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Kikuchi, W. Kai, A. Hosokawa, N. Mizuno, H. Suetake, K. Asahina, and Y. Suzuki The Sex-Determining Locus in the Tiger Pufferfish, Takifugu rubripes Genetics, April 1, 2007; 175(4): 2039 - 2042. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Semon and K. H. Wolfe Rearrangement Rate following the Whole-Genome Duplication in Teleosts Mol. Biol. Evol., March 1, 2007; 24(3): 860 - 867. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Sekino and M. Hara Linkage Maps for the Pacific Abalone (Genus Haliotis) Based on Microsatellite DNA Markers Genetics, February 1, 2007; 175(2): 945 - 958. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. M. Wang, Z. Y. Zhu, L. C. Lo, F. Feng, G. Lin, W. T. Yang, J. Li, and G. H. Yue A Microsatellite Linkage Map of Barramundi, Lates calcarifer Genetics, February 1, 2007; 175(2): 907 - 915. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Huang, Y. Zhao, C. S. Haley, S. Hu, J. Hao, C. Wu, and N. Li A Genetic and Cytogenetic Map for the Duck (Anas platyrhynchos) Genetics, May 1, 2006; 173(1): 287 - 296. [Abstract] [Full Text] [PDF]
|
|