- THIS ARTICLE
- Full Text
- Full Text (PDF)
-
All Versions of this Article:
genetics.104.032516v1
170/1/127 most recent - Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Email this article to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Sousa-Neves, R.
- Articles by Marsh, J. L.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Sousa-Neves, R.
- Articles by Marsh, J. L.
Originally published as Genetics Published Articles Ahead of Print on September 30, 2004.
Genetics, Vol. 170, 127-138, May 2005, Copyright © 2005
doi:10.1534/genetics.104.032516
High-Resolution Mapping of the Drosophila Fourth Chromosome Using Site-Directed Terminal Deficiencies
Rui Sousa-Neves*,1,
Tamas Lukacsovich*,
Claudia Mieko Mizutani
,
John Locke
,
Lynn Podemski and
J. Lawrence Marsh*
* Department of Developmental and Cell Biology and the Developmental Biology Center, University of California, Irvine, California 92697
Section of Cell and Developmental Biology, University of California, San Diego, California 92093-0349
Department of Biological Sciences, University of Alberta, Edmonton, Alberta T6G 2E9, Canada
1 Corresponding author: Department of Developmental and Cell Biology, Room 4444, McGaugh Hall, University of California, Irvine, CA 92697.
E-mail: nevesr{at}uci.edu
For more than 80 years, the euchromatic right arm of the Drosophila fourth chromosome (101F-102F) has been one of the least genetically accessible regions of the fly genome despite the fact that many important genes reside there. To improve the mapping of genes on the fourth chromosome, we describe a strategy to generate targeted deficiencies and we describe 13 deficiencies that subdivide the 300 kb between the cytological coordinates 102A6 and 102C1 into five discrete regions plus a 200-kb region from 102C1 to 102D6. Together these deficiencies substantially improve the mapping capabilities for mutant loci on the fourth chromosome.
This article has been cited by other articles:
 |
|
 |
|
  K. A. Haynes, E. Gracheva, and S. C. R. Elgin A Distinct Type of Heterochromatin Within Drosophila melanogaster Chromosome 4 Genetics, March 1, 2007; 175(3): 1539 - 1542. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. C. Ayoob, J. R. Terman, and A. L. Kolodkin Drosophila Plexin B is a Sema-2a receptor required for axon guidance Development, June 1, 2006; 133(11): 2125 - 2135. [Abstract] [Full Text] [PDF]
|
|