help button home button Genetics AJP: Cell Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Yildiz, O.
Right arrow Articles by Sekelsky, J. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yildiz, O.
Right arrow Articles by Sekelsky, J. J.
Genetics, Vol. 167, 263-273, May 2004, Copyright © 2004

Mutational Analysis of the Drosophila DNA Repair and Recombination Gene mei-9

Özlem Yildiza, Hutton Kearneya, Benjamin C. Kramera, and Jeff J. Sekelskya,b
a Department of Biology, University of North Carolina, Chapel Hill, North Carolina 27599
b Program in Molecular Biology and Biotechnology, University of North Carolina, Chapel Hill, North Carolina 27599

Corresponding author: Jeff J. Sekelsky, 303 Fordham Hall, University of North Carolina, Chapel Hill, NC 27599., sekelsky{at}unc.edu (E-mail)

Communicating editor: K. G. GOLIC

Drosophila mei-9 is essential for several DNA repair and recombination pathways, including nucleotide excision repair (NER), interstrand crosslink repair, and meiotic recombination. To better understand the role of MEI-9 in these processes, we characterized 10 unique mutant alleles of mei-9. These include a P-element insertion that disrupts repair functions but not the meiotic function; three nonsense mutations, one of which has nearly wild-type levels of protein; three missense mutations, one of which disrupts the meiotic function but not repair functions; two small in-frame deletions; and one frameshift.




This article has been cited by other articles:


Home page
 Proc. Natl. Acad. Sci. USAHome page
E. R. Taylor and C. H. McGowan
Cleavage mechanism of human Mus81-Eme1 acting on Holliday-junction structures
PNAS, March 11, 2008; 105(10): 3757 - 3762.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
M. McVey, S. L. Andersen, Y. Broze, and J. Sekelsky
Multiple Functions of Drosophila BLM Helicase in Maintenance of Genome Stability
Genetics, August 1, 2007; 176(4): 1979 - 1992.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
K. Trowbridge, K. McKim, S. J. Brill, and J. Sekelsky
Synthetic Lethality of Drosophila in the Absence of the MUS81 Endonuclease and the DmBlm Helicase Is Associated With Elevated Apoptosis
Genetics, August 1, 2007; 176(4): 1993 - 2001.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
S. J. Radford, S. McMahan, H. L. Blanton, and J. Sekelsky
Heteroduplex DNA in Meiotic Recombination in Drosophila mei-9 Mutants
Genetics, May 1, 2007; 176(1): 63 - 72.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
A. J. Wijeratne, C. Chen, W. Zhang, L. Timofejeva, and H. Ma
The Arabidopsis thaliana PARTING DANCERS Gene Encoding a Novel Protein Is Required for Normal Meiotic Homologous Recombination
Mol. Biol. Cell, March 1, 2006; 17(3): 1331 - 1343.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
S. J. Radford, E. Goley, K. Baxter, S. McMahan, and J. Sekelsky
Drosophila ERCC1 Is Required for a Subset of MEI-9-Dependent Meiotic Crossovers
Genetics, August 1, 2005; 170(4): 1737 - 1745.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2004 by the Genetics Society of America.