The Dominance of the Herbicide Resistance Cost in Several Arabidopsis thaliana Mutant Lines

Corresponding author: Fabrice Roux, 17 rue Sully, Institut National de la Recherche Agronomique, BP86510, 21065 Dijon Cedex, France., roux{at}dijon.inra.fr (E-mail)

Communicating editor: J. BERGELSON

Resistance evolution depends upon the balance between advantage and disadvantage (cost) conferred in treated and untreated areas. By analyzing morphological characters and simple fitness components, the cost associated with each of eight herbicide resistance alleles (acetolactate synthase, cellulose synthase, and auxin-induced target genes) was studied in the model plant Arabidopsis thaliana. The use of allele-specific PCR to discriminate between heterozygous and homozygous plants was used to provide insights into the dominance of the resistance cost, a parameter rarely described. Morphological characters appear more sensitive than fitness (seed production) because 6 vs. 4 differences between resistant and sensitive homozygous plants were detected, respectively. Dominance levels for the fitness cost ranged from recessivity (csr1-1, ixr1-2, and axr1-3) to dominance (axr2-1) to underdominance (aux1-7). Furthermore, the dominance level of the herbicide resistance trait did not predict the dominance level of the cost of resistance. The relationship of our results to theoretical predictions of dominance and the consequences of fitness cost and its dominance in resistance management are discussed.

This article has been cited by other articles:

				Q. Yu, A. Collavo, M.-Q. Zheng, M. Owen, M. Sattin, and S. B. Powles Diversity of Acetyl-Coenzyme A Carboxylase Mutations in Resistant Lolium Populations: Evaluation Using Clethodim Plant Physiology, October 1, 2007; 145(2): 547 - 558. [Abstract] [Full Text] [PDF]

				Y. Manabe, N. Tinker, A. Colville, and B. Miki CSR1, the Sole Target of Imidazolinone Herbicide in Arabidopsis thaliana Plant Cell Physiol., September 1, 2007; 48(9): 1340 - 1358. [Abstract] [Full Text] [PDF]

				F. Roux, S. Giancola, S. Durand, and X. Reboud Building of an Experimental Cline With Arabidopsis thaliana to Estimate Herbicide Fitness Cost Genetics, June 1, 2006; 173(2): 1023 - 1031. [Abstract] [Full Text] [PDF]

				F. Roux, C. Camilleri, S. Giancola, D. Brunel, and X. Reboud Epistatic Interactions Among Herbicide Resistances in Arabidopsis thaliana: The Fitness Cost of Multiresistance Genetics, November 1, 2005; 171(3): 1277 - 1288. [Abstract] [Full Text] [PDF]