Distinguishing the Hitchhiking and Background Selection Models

Distinguishing the Hitchhiking and Background Selection Models

Hideki Innan^a and Wolfgang Stephan^b
^a Human Genetics Center, University of Texas Health Science Center, Houston, Texas 77030
^b Section of Evolutionary Biology, Department of Biology II, University of Munich, 80333 Munich, Germany

Corresponding author: Hideki Innan, School of Public Health, University of Texas Health Science Center, 1200 Hermann Pressler Dr., Houston, TX 77030., hideki.innan{at}uth.tmc.edu (E-mail)

Communicating editor: M. AGUADÉ

A simple method to distinguish hitchhiking and background selectionis proposed. It is based on the observation that these modelsmake different predictions about the average level of nucleotidediversity in regions of low recombination. The method is appliedto data from Drosophila melanogaster and two highly selfingtomato species.

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