Genetics, Vol. 165, 1623-1628, November 2003, Copyright © 2003

The EGL-13 SOX Domain Transcription Factor Affects the Uterine {pi} Cell Lineages in Caenorhabditis elegans

Hediye Nese Cinara, Keri L. Richardsa, Kavita S. Oommenb, and Anna P. Newmana,b
a Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030
b Program in Developmental Biology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030

Corresponding author: Anna P. Newman, Department of Biochemistry and Molecular Biology, MS 319B, One Baylor Plaza, Houston, TX 77030., anewman{at}bcm.tmc.edu (E-mail)

Communicating editor: B. J. MEYER

We isolated egl-13 mutants in which the {pi} cells of the Caenorhabditis elegans uterus initially appeared to develop normally but then underwent an extra round of cell division. The data suggest that egl-13 is required for maintenance of the {pi} cell fate.





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