Distribution of Temperature Tolerance Quantitative Trait Loci in Arctic Charr (Salvelinus alpinus) and Inferred Homologies in Rainbow Trout (Oncorhynchus mykiss)

Distribution of Temperature Tolerance Quantitative Trait Loci in Arctic Charr (Salvelinus alpinus) and Inferred Homologies in Rainbow Trout (Oncorhynchus mykiss)

Ildiko M. L. Somorjai^a, Roy G. Danzmann^a, and Moira M. Ferguson^a
^a Department of Zoology, University of Guelph, Guelph, Ontario N1G 2W1, Canada

Corresponding author: Moira M. Ferguson, University of Guelph, 50 Stone Rd. East, Guelph, ON N1G 2W1, Canada., mmfergus{at}uoguelph.ca (E-mail)

Communicating editor: M. NOOR

We searched for quantitative trait loci (QTL) affecting uppertemperature tolerance (UTT) in crosses between the Nauyuk Lakeand Fraser River strains of Arctic charr (Salvelinus alpinus)using survival analysis. Two QTL were detected by using twomicrosatellite markers after correcting for experiment-wideerror. A comparative mapping approach localized these two QTLto homologous linkage groups containing UTT QTL in rainbow trout(Oncorhynchus mykiss). Additional marginal associations weredetected in several families in regions homologous to thosewith QTL in rainbow trout. Thus, the genes underlying UTT QTLmay antedate the divergence of these two species, which occurredby $~$ 16 MYA. The data also indicate that one pair of homeologs(ancestrally duplicated chromosomal segments) have containedQTL in Arctic charr since the evolution of salmonids from atetraploid ancestor 25–100 MYA. This study representsone of the first examples of comparative QTL mapping in an animalpolyploid group and illustrates the fate of QTL after genomeduplication and reorganization.

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