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Corresponding author: Stephen A. Osmani, The Ohio State University, 804 Riffe Bldg., 496 W. 12th Ave., Columbus, OH 43210. E-mail osmani.2@osu.edu
Communicating editor: B. ANDREWS
phoB background. Double-deleted ascospores were able to germinate but had a limited capacity for nuclear division, suggesting a cell cycle defect. Longer germination revealed morphological defects. The temperature-sensitive phoA allele caused both nuclear division and polarity defects at restrictive temperature, which could be complemented by expression of mammalian CDK5. Therefore, an essential function exists in A. nidulans for the Pho85-like kinase pair PHOA and PHOB, which may involve cell cycle control and morphogenesis.
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