Mathematical Issues Arising From the Directed Mutation Controversy

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Mathematical Issues Arising From the Directed Mutation Controversy

Qi Zheng^a
^a Department of Statistics, Texas A&M University, College Station, Texas 77843

Corresponding author: Qi Zheng

Communicating editor: Y.-X. FU

During the past 14 years or so a large body of new evidencethat supposedly supports the directed mutation hypothesis hasaccumulated. Interpretation of some of the evidence dependson mathematical reasoning, which can be subtler than it appearsat first sight. This article attempts to clarify some of themathematical issues arising from the directed mutation controversy,thereby offering alternative interpretations of some of theevidence.