Genetics, Vol. 164, 373-379, May 2003, Copyright © 2003

Mathematical Issues Arising From the Directed Mutation Controversy

Qi Zhenga
a Department of Statistics, Texas A&M University, College Station, Texas 77843

Corresponding author: Qi Zheng

Communicating editor: Y.-X. FU

During the past 14 years or so a large body of new evidence that supposedly supports the directed mutation hypothesis has accumulated. Interpretation of some of the evidence depends on mathematical reasoning, which can be subtler than it appears at first sight. This article attempts to clarify some of the mathematical issues arising from the directed mutation controversy, thereby offering alternative interpretations of some of the evidence.