Recessive Mutations and the Maintenance of Sex in Structured Populations

Corresponding author: Aneil F. Agrawal, 1001 E. 3rd St., Department of Biology, Indiana University, Bloomington, IN 47405-3700., aagrawal{at}bio.indiana.edu (E-mail)

Communicating editor: M. J. SIMMONS

The evolutionary maintenance of sexual reproduction remains a controversial problem. It was recently shown that recessive deleterious mutations create differences in the mutation load of sexual vs. asexual populations. Here we show that low levels of population structure or inbreeding can greatly enhance the importance of recessive deleterious mutations in the context of sexual vs. asexual populations. With population structure, the cost of sex can be substantially reduced or even eliminated for realistic levels of dominance.

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