help button home button Genetics Mol Pharm
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Auger, D. L.
Right arrow Articles by Birchler, J. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Auger, D. L.
Right arrow Articles by Birchler, J. A.
Genetics, Vol. 157, 1711-1721, April 2001, Copyright © 2001

Nuclear Gene Dosage Effects Upon the Expression of Maize Mitochondrial Genes

Donald L. Augera, Kathleen J. Newtona, and James A. Birchlera
a Division of Biological Sciences, University of Missouri, Columbia, Missouri 65211

Corresponding author: James A. Birchler, Division of Biological Sciences, 117 Tucker Hall, University of Missouri, Columbia, MO 65211., birchlerj{at}missouri.edu (E-mail)

Communicating editor: V. L. CHANDLER

Each mitochondrion possesses a genome that encodes some of its own components. The nucleus encodes most of the mitochondrial proteins, including the polymerases and factors that regulate the expression of mitochondrial genes. Little is known about the number or location of these nuclear factors. B-A translocations were used to create dosage series for 14 different chromosome arms in maize plants with normal cytoplasm. The presence of one or more regulatory factors on a chromosome arm was indicated when variation of its dosage resulted in the alteration in the amount of a mitochondrial transcript. We used quantitative Northern analysis to assay the transcript levels of three mitochondrially encoded components of the cytochrome c oxidase complex (cox1, cox2, and cox3). Data for a nuclearly encoded component (cox5b) and for two mitochondrial genes that are unrelated to cytochrome c oxidase, ATP synthase {alpha}-subunit and 18S rRNA, were also determined. Two tissues, embryo and endosperm, were compared and most effects were found to be tissue specific. Significantly, the array of dosage effects upon mitochondrial genes was similar to what had been previously found for nuclear genes. These results support the concept that although mitochondrial genes are prokaryotic in origin, their regulation has been extensively integrated into the eukaryotic cell.




This article has been cited by other articles:


Home page
 GeneticsHome page
W. F. Sheridan and D. L. Auger
Construction and Uses of New Compound B-A-A Maize Chromosome Translocations
Genetics, December 1, 2006; 174(4): 1755 - 1765.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
D. L. Auger, A. D. Gray, T. S. Ream, A. Kato, E. H. Coe Jr., and J. A. Birchler
Nonadditive Gene Expression in Diploid and Triploid Hybrids of Maize
Genetics, January 1, 2005; 169(1): 389 - 397.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
J. A. Birchler, D. L. Auger, and N. C. Riddle
In Search of the Molecular Basis of Heterosis
PLANT CELL, October 1, 2003; 15(10): 2236 - 2239.
[Full Text] [PDF]

Home page
 Plant Physiol.Home page
M. A. R. Milla, E. Butler, A. R. Huete, C. F. Wilson, O. Anderson, and J. P. Gustafson
Expressed Sequence Tag-Based Gene Expression Analysis under Aluminum Stress in Rye
Plant Physiology, December 1, 2002; 130(4): 1706 - 1716.
[Abstract] [Full Text] [PDF]

Home page
 J HeredHome page
D. L. Auger and J. A. Birchler
Maize Tertiary Trisomic Stocks Derived From B-A Translocations
J. Hered., January 1, 2002; 93(1): 42 - 47.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2001 by the Genetics Society of America.