Genetics, Vol. 155, 451-462, May 2000, Copyright © 2000

The Coalescent With Gene Conversion

Carsten Wiufa and Jotun Heinb
a Department of Statistics, University of Oxford, Oxford OX1 3TG, England
b Institute of Biological Sciences, University of Aarhus, 8000 Aarhus C, Denmark

Corresponding author: Carsten Wiuf, Department of Statistics, University of Oxford, 1 S. Parks Rd., Oxford, OX1 3TG, England., wiuf{at}stats.ox.ac.uk (E-mail)

Communicating editor: A. G. CLARK

In this article we develop a coalescent model with intralocus gene conversion. The distribution of the tract length is geometric in concordance with results published in the literature. We derive a simulation scheme and deduce a number of analytical results for this coalescent with gene conversion. We compare patterns of variability in samples simulated according to the coalescent with recombination with similar patterns simulated according to the coalescent with gene conversion alone. Further, an expression for the expected number of topology shifts in a sample of present-day sequences caused by gene conversion events is derived.





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