Genetics, Vol. 148, 1535-1538, April 1998, Copyright © 1998

A New Look at Old Mutants of T4 DNA Polymerase

Nancy G. Nossala
a Laboratory of Molecular and Cellular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892-0830

Corresponding author: Nancy G. Nossal, Bldg. 8, Rm. 2A-19, National Institutes of Health, Bethesda, MD 20892-0830, ngn{at}helix.nih.gov (E-mail).

The DNA polymerase and nuclease activities of bacteriophage T4 DNA polymerase mutants are discussed in the context of the crystal structure of the closely related bacteriophage RB69 DNA polymerase.





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