- THIS ARTICLE
- Full Text (PDF)
- Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Ranz, J. M.
- Articles by Ruiz, A.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Ranz, J. M.
- Articles by Ruiz, A.
Genetics, Vol 145, 281-295, Copyright © 1997
INVESTIGATIONS |
Chromosomal Homology and Molecular Organization of Muller's Elements D and E in the Drosophila repleta Species Group
J. M. Ranz, C. Segarra and A. Ruiz
Departament de Genetica i de Microbiologia, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
Thirty-three DNA clones containing protein-coding genes have been used for in situ hybridization to the polytene chromosomes of two Drosophila repleta group species, D. repleta and D. buzzatii. Twenty-six clones gave positive results allowing the precise localization of 26 genes and the tentative identification of another nine. The results were fully consistent with the currently accepted chromosomal homologies and in no case was evidence for reciprocal translocations or pericentric inversions found. Most of the genes mapped to chromosomes 2 and 4 that are homologous, respectively, to chromosome arms 3R and 3L of D. melanogaster (Muller's elements E and D). The comparison of the molecular organization of these two elements between D. melanogaster and D. repleta (two species that belong to different subgenera and diverged some 62 million years ago) showed an extensive reorganization via paracentric inversions. Using a maximum likelihood procedure, we estimated that 130 paracentric inversions have become fixed in element E after the divergence of the two lineages. Therefore, the evolution rate for element E is approximately one inversion per million years. This value is comparable to previous estimates of the rate of evolution of chromosome X and yields an estimate of 4.5 inversions per million years for the whole Drosophila genome.
This article has been cited by other articles:
 |
|
 |
|
  A. Bhutkar, S. W. Schaeffer, S. M. Russo, M. Xu, T. F. Smith, and W. M. Gelbart Chromosomal Rearrangement Inferred From Comparisons of 12 Drosophila Genomes Genetics, July 1, 2008; 179(3): 1657 - 1680. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Gonzalez, F. Casals, and A. Ruiz Testing Chromosomal Phylogenies and Inversion Breakpoint Reuse in Drosophila Genetics, January 1, 2007; 175(1): 167 - 177. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Bartolome and B. Charlesworth Rates and Patterns of Chromosomal Evolution in Drosophila pseudoobscura and D. miranda Genetics, June 1, 2006; 173(2): 779 - 791. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Gonzalez, M. Nefedov, I. Bosdet, F. Casals, O. Calvete, A. Delprat, H. Shin, R. Chiu, C. Mathewson, N. Wye, et al. A BAC-based physical map of the Drosophila buzzatii genome Genome Res., June 1, 2005; 15(6): 885 - 892. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Richards, Y. Liu, B. R. Bettencourt, P. Hradecky, S. Letovsky, R. Nielsen, K. Thornton, M. J. Hubisz, R. Chen, R. P. Meisel, et al. Comparative genome sequencing of Drosophila pseudoobscura: Chromosomal, gene, and cis-element evolution Genome Res., January 1, 2005; 15(1): 1 - 18. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Piccinali, M. Aguade, and E. Hasson Comparative Molecular Population Genetics of the Xdh Locus in the Cactophilic Sibling Species Drosophila buzzatii and D. koepferae Mol. Biol. Evol., January 1, 2004; 21(1): 141 - 152. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Negre, J. M. Ranz, F. Casals, M. Caceres, and A. Ruiz A New Split of the Hox Gene Complex in Drosophila: Relocation and Evolution of the Gene labial Mol. Biol. Evol., December 1, 2003; 20(12): 2042 - 2054. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. W. Schaeffer, M. J. Bernhardt, and W. W. Anderson Evolutionary Rearrangement of the Amylase Genomic Regions Between Drosophila melanogaster and Drosophila pseudoobscura J. Hered., November 1, 2003; 94(6): 464 - 471. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Gonzalez, J. M. Ranz, and A. Ruiz Chromosomal Elements Evolve at Different Rates in the Drosophila Genome Genetics, July 1, 2002; 161(3): 1137 - 1154. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Rodriguez, R. Piccinali, E. Levy, and E. Hasson Gametic Associations Between Inversion and Allozyme Polymorphisms in Drosophila buzzatii J. Hered., September 1, 2001; 92(5): 382 - 391. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Ranz, F. Casals, and A. Ruiz How Malleable is the Eukaryotic Genome? Extreme Rate of Chromosomal Rearrangement in the Genus Drosophila Genome Res., February 1, 2001; 11(2): 230 - 239. [Abstract] [Full Text]
|
|
|
|
|
|
H. Laayouni, M. Santos, and A. Fontdevila Toward a Physical Map of Drosophila buzzatii: Use of Randomly Amplified Polymorphic DNA Polymorphisms and Sequence-Tagged Site Landmarks Genetics, December 1, 2000; 156(4): 1797 - 1816. [Abstract] [Full Text]
|
|
|
|
|
|
A. Navarro, A. Barbadilla, and A. Ruiz Effect of Inversion Polymorphism on the Neutral Nucleotide Variability of Linked Chromosomal Regions in Drosophila Genetics, June 1, 2000; 155(2): 685 - 698. [Abstract] [Full Text]
|
|
|
|
 |
|
 M. Cáceres, J. M. Ranz, A. Barbadilla, M. Long, and A. Ruiz Generation of a Widespread Drosophila Inversion by a Transposable Element Science, July 16, 1999; 285(5426): 415 - 418. [Abstract] [Full Text]
|
|