- THIS ARTICLE
- Full Text (PDF)
- Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Garcia, B. A.
- Articles by Powell, J. R.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Garcia, B. A.
- Articles by Powell, J. R.
Genetics, Vol 143, 1313-1320, Copyright © 1996
INVESTIGATIONS |
Inversion Monophyly in African Anopheline Malaria Vectors
B. A. Garcia, A. Caccone, K. D. Mathiopoulos and J. R. Powell
Department of Biology, Yale University, New Haven, Connecticut 06520-8104, Catedra de Quimica Biologica, Facultad de Ciencias Medicas, Universidad Nacional de Cordoba, Cordoba, Argentina
The African Anopheles gambiae complex of six sibling species has many polymorphic and fixed paracentric inversions detectable in polytene chromosomes. These have been used to infer phylogenetic relationships as classically done with Drosophila. Two species, A. gambiae and A. merus, were thought to be sister taxa based on a shared X inversion designated X(ag). Recent DNA data have conflicted with this phylogenetic inference as they have supported a sister taxa relationship of A. gambiae and A. arabiensis. A possible explanation is that the X(ag) is not monophyletic. Here we present data from a gene (soluble guanylate cyclase) within the X(ag) that strongly supports the monophyly of the X(ag). We conjecture that introgression may be occurring between the widely sympatric species A. gambiae and A. arabiensis and that the previous DNA phylogenies have been detecting the introgression. Evidently, introgression is not uniform across the genome, and species-specific regions, like the X-chromosome inversions, do not introgress probably due to selective elimination in hybrids and backcrosses.
This article has been cited by other articles:
 |
|
 |
|
  M. A. SLOTMAN, M. M. MENDEZ, A. D. TORRE, G. DOLO, Y. T. TOURE, and A. CACCONE GENETIC DIFFERENTIATION BETWEEN THE BAMAKO AND SAVANNA CHROMOSOMAL FORMS OF ANOPHELES GAMBIAE AS INDICATED BY AMPLIFIED FRAGMENT LENGTH POLYMORPHISM ANALYSIS Am J Trop Med Hyg, April 1, 2006; 74(4): 641 - 648. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Zhong, E. A. Temu, T. Guda, L. Gouagna, D. Menge, A. Pai, J. Githure, J. C. Beier, and G. Yan Dynamics of Gene Introgression in the African Malaria Vector Anopheles gambiae Genetics, April 1, 2006; 172(4): 2359 - 2365. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. SLOTMAN, A. D. TORRE, M. CALZETTA, and J. R. POWELL DIFFERENTIAL INTROGRESSION OF CHROMSOMAL REGIONS BETWEEN ANOPHELES GAMBIAE AND AN. ARABIENSIS Am J Trop Med Hyg, August 1, 2005; 73(2): 326 - 335. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. D. Stump, J. A. Shoener, C. Costantini, N. Sagnon, and N. J. Besansky Sex-Linked Differentiation Between Incipient Species of Anopheles gambiae Genetics, March 1, 2005; 169(3): 1509 - 1519. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. J. Besansky, J. Krzywinski, T. Lehmann, F. Simard, M. Kern, O. Mukabayire, D. Fontenille, Y. Toure, and N'F. Sagnon Semipermeable species boundaries between Anopheles gambiae and Anopheles arabiensis: Evidence from multilocus DNA sequence variation PNAS, September 16, 2003; 100(19): 10818 - 10823. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Caccone, G.-S. Min, and J. R. Powell Multiple Origins of Cytologically Identical Chromosome Inversions in the Anopheles gambiae Complex Genetics, October 1, 1998; 150(2): 807 - 814. [Abstract] [Full Text]
|
|