- THIS ARTICLE
- Full Text (PDF)
- Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Lawrence, J. G.
- Articles by Roth, J. R.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Lawrence, J. G.
- Articles by Roth, J. R.
Genetics, Vol 142, 11-24, Copyright © 1996
INVESTIGATIONS |
Evolution of Coenzyme B(12) Synthesis Among Enteric Bacteria: Evidence for Loss and Reacquisition of a Multigene Complex
J. G. Lawrence and J. R. Roth
Department of Biology, University of Utah, Salt Lake City, Utah 84112
We have examined the distribution of cobalamin (coenzyme B(12)) synthetic ability and cobalamin-dependent metabolism among enteric bacteria. Most species of enteric bacteria tested synthesize cobalamin under both aerobic and anaerobic conditions and ferment glycerol in a cobalamin-dependent fashion. The group of species including Escherichia coli and Salmonella typhimurium cannot ferment glycerol. E. coli strains cannot synthesize cobalamin de novo, and Salmonella spp. synthesize cobalamin only under anaerobic conditions. In addition, the cobalamin synthetic genes of Salmonella spp. (cob) show a regulatory pattern different from that of other enteric taxa tested. We propose that the cobalamin synthetic genes, as well as genes providing cobalamin-dependent diol dehydratase, were lost by a common ancestor of E. coli and Salmonella spp. and were reintroduced as a single fragment into the Salmonella lineage from an exogenous source. Consistent with this hypothesis, the S. typhimurium cob genes do not hybridize with the genomes of other enteric species. The Salmonella cob operon may represent a class of genes characterized by periodic loss and reacquisition by host genomes. This process may be an important aspect of bacterial population genetics and evolution.
This article has been cited by other articles:
 |
|
 |
|
  A. Iguchi, N. R. Thomson, Y. Ogura, D. Saunders, T. Ooka, I. R. Henderson, D. Harris, M. Asadulghani, K. Kurokawa, P. Dean, et al. Complete Genome Sequence and Comparative Genome Analysis of Enteropathogenic Escherichia coli O127:H6 Strain E2348/69 J. Bacteriol., January 1, 2009; 191(1): 347 - 354. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. A. Rasko, M. J. Rosovitz, G. S. A. Myers, E. F. Mongodin, W. F. Fricke, P. Gajer, J. Crabtree, M. Sebaihia, N. R. Thomson, R. Chaudhuri, et al. The Pangenome Structure of Escherichia coli: Comparative Genomic Analysis of E. coli Commensal and Pathogenic Isolates J. Bacteriol., October 15, 2008; 190(20): 6881 - 6893. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. D. Sriramulu, M. Liang, D. Hernandez-Romero, E. Raux-Deery, H. Lunsdorf, J. B. Parsons, M. J. Warren, and M. B. Prentice Lactobacillus reuteri DSM 20016 Produces Cobalamin-Dependent Diol Dehydratase in Metabolosomes and Metabolizes 1,2-Propanediol by Disproportionation J. Bacteriol., July 1, 2008; 190(13): 4559 - 4567. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. B. Parsons, S. D. Dinesh, E. Deery, H. K. Leech, A. A. Brindley, D. Heldt, S. Frank, C. M. Smales, H. Lunsdorf, A. Rambach, et al. Biochemical and Structural Insights into Bacterial Organelle Form and Biogenesis J. Biol. Chem., May 23, 2008; 283(21): 14366 - 14375. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Brzuszkiewicz, H. Bruggemann, H. Liesegang, M. Emmerth, T. Olschlager, G. Nagy, K. Albermann, C. Wagner, C. Buchrieser, L. Emody, et al. How to become a uropathogen: Comparative genomic analysis of extraintestinal pathogenic Escherichia coli strains PNAS, August 22, 2006; 103(34): 12879 - 12884. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. P. Scott, J. C. Martin, G. Campbell, C.-D. Mayer, and H. J. Flint Whole-Genome Transcription Profiling Reveals Genes Up-Regulated by Growth on Fucose in the Human Gut Bacterium "Roseburia inulinivorans". J. Bacteriol., June 1, 2006; 188(12): 4340 - 4349. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. A. Maggio-Hall and J. C. Escalante-Semerena {alpha}-5,6-Dimethylbenzimidazole adenine dinucleotide ({alpha}-DAD), a putative new intermediate of coenzyme B12 biosynthesis in Salmonella typhimurium Microbiology, April 1, 2003; 149(4): 983 - 990. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Kotetishvili, O. C. Stine, A. Kreger, J. G. Morris Jr., and A. Sulakvelidze Multilocus Sequence Typing for Characterization of Clinical and Environmental Salmonella Strains J. Clin. Microbiol., May 1, 2002; 40(5): 1626 - 1635. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. D. Havemann, E. M. Sampson, and T. A. Bobik PduA Is a Shell Protein of Polyhedral Organelles Involved in Coenzyme B12-Dependent Degradation of 1,2-Propanediol in Salmonella enterica Serovar Typhimurium LT2 J. Bacteriol., March 1, 2002; 184(5): 1253 - 1261. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. de Vries and W. Wackernagel Integration of foreign DNA during natural transformation of Acinetobacter sp. by homology-facilitated illegitimate recombination PNAS, February 19, 2002; 99(4): 2094 - 2099. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H.-S. Park and H.-S. Kim Genetic and Structural Organization of the Aminophenol Catabolic Operon and Its Implication for Evolutionary Process J. Bacteriol., September 1, 2001; 183(17): 5074 - 5081. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Price-Carter, J. Tingey, T. A. Bobik, and J. R. Roth The Alternative Electron Acceptor Tetrathionate Supports B12-Dependent Anaerobic Growth of Salmonella enterica Serovar Typhimurium on Ethanolamine or 1,2-Propanediol J. Bacteriol., April 15, 2001; 183(8): 2463 - 2475. [Abstract] [Full Text]
|
|
|
|
|
|
M. M. Kolko, L. A. Kapetanovich, and J. G. Lawrence Alternative Pathways for Siroheme Synthesis in Klebsiella aerogenes J. Bacteriol., January 1, 2001; 183(1): 328 - 335. [Abstract] [Full Text]
|
|
|
|
|
|
T. A. Seiflein and J. G. Lawrence Methionine-to-Cysteine Recycling in Klebsiella aerogenes J. Bacteriol., January 1, 2001; 183(1): 336 - 346. [Abstract] [Full Text]
|
|
|
|
|
|
T. A. Bobik, G. D. Havemann, R. J. Busch, D. S. Williams, and H. C. Aldrich The Propanediol Utilization (pdu) Operon of Salmonella enterica Serovar Typhimurium LT2 Includes Genes Necessary for Formation of Polyhedral Organelles Involved in Coenzyme B12-Dependent 1,2-Propanediol Degradation J. Bacteriol., October 1, 1999; 181(19): 5967 - 5975. [Abstract] [Full Text]
|
|
|
|
|
|
E. Kofoid, C. Rappleye, I. Stojiljkovic, and J. Roth The 17-Gene Ethanolamine (eut) Operon of Salmonella typhimurium Encodes Five Homologues of Carboxysome Shell Proteins J. Bacteriol., September 1, 1999; 181(17): 5317 - 5329. [Abstract] [Full Text]
|
|
|
|
 |
|
 M. McClelland and R. K. Wilson Comparison of Sample Sequences of the Salmonella typhi Genome to the Sequence of the Complete Escherichia coli K-12 Genome Infect. Immun., September 1, 1998; 66(9): 4305 - 4312. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. K. B. Berlyn Linkage Map of Escherichia coli K-12, Edition 10: The Traditional Map Microbiol. Mol. Biol. Rev., September 1, 1998; 62(3): 814 - 984. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Roper, E. Raux, A. A. Brindley, H. L. Schubert, S. E. Gharbia, H. N. Shah, and M. J. Warren The Enigma of Cobalamin (Vitamin B12) Biosynthesis in Porphyromonas gingivalis. IDENTIFICATION AND CHARACTERIZATION OF A FUNCTIONAL CORRIN PATHWAY J. Biol. Chem., December 15, 2000; 275(51): 40316 - 40323. [Abstract] [Full Text] [PDF]
|
|