- THIS ARTICLE
- Full Text (PDF)
- Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Yonesaki, T.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Yonesaki, T.
Genetics, Vol 138, 247-252, Copyright © 1994
INVESTIGATIONS |
Involvement of a Replicative DNA Helicase of Bacteriophage T4 in DNA Recombination
T. Yonesaki
Department of Biology, College of General Education, Osaka University, Osaka 560, Japan
Bacteriophage T4 gene 41 encodes a replicative DNA helicase that is a subunit of the primosome which is essential for lagging-strand DNA synthesis. A mutation, rrh, was generated and selected in the helicase gene on the basis of limited DNA replication that ceases early. The survival of ultraviolet-irradiated phage and the frequency of genetic recombination are reduced by rrh. In addition, rrh diminishes the production of concatemeric DNA. These results strongly suggest that the gene 41 replicative helicase participates in DNA recombination.
This article has been cited by other articles:
![]() |
F. A. Kadyrov and J. W. Drake Properties of Bacteriophage T4 Proteins Deficient in Replication Repair J. Biol. Chem., June 27, 2003; 278(27): 25247 - 25255. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. S. Miller, E. Kutter, G. Mosig, F. Arisaka, T. Kunisawa, and W. Ruger Bacteriophage T4 Genome Microbiol. Mol. Biol. Rev., March 1, 2003; 67(1): 86 - 156. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. E. Jones, T. C. Mueser, K. C. Dudas, K. N. Kreuzer, and N. G. Nossal Bacteriophage T4 gene 41 helicase and gene 59 helicase-loading protein: A versatile couple with roles in replication and recombination PNAS, July 17, 2001; 98(15): 8312 - 8318. [Abstract] [Full Text] [PDF] |
||||
![]() |
J E Mueller, J Clyman, Y J Huang, M M Parker, and M Belfort Intron mobility in phage T4 occurs in the context of recombination-dependent DNA replication by way of multiple pathways. Genes & Dev., February 1, 1996; 10(3): 351 - 364. [Abstract] [PDF] |
||||
![]() |
K. Tarumi and T. Yonesaki Functional Interactions of Gene 32, 41, and 59 Proteins of Bacteriophage T4 J. Biol. Chem., February 10, 1995; 270(6): 2614 - 2619. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. E. Jones, T. C. Mueser, and N. G. Nossal Interaction of the Bacteriophage T4 Gene 59 Helicase Loading Protein and Gene 41 Helicase with Each Other and with Fork, Flap, and Cruciform DNA J. Biol. Chem., August 25, 2000; 275(35): 27145 - 27154. [Abstract] [Full Text] [PDF] |
||||



