- THIS ARTICLE
- Full Text (PDF)
- Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Modi, R. I.
- Articles by Adams, J.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Modi, R. I.
- Articles by Adams, J.
Genetics, Vol 130, 241-249, Copyright © 1992
INVESTIGATIONS |
Genetic Changes Accompanying Increased Fitness in Evolving Populations of Escherichia coli
R. I. Modi, L. H. Castilla, S. Puskas-Rozsa, R. B. Helling and J. Adams
Present address: Cadila Laboratories, Ahmedabad-380008, Gujarat, India.
Two populations of Escherichia coli, each initiated with a single clone containing a derivative of the plasmid pBR322, were maintained for long periods in glucose-limited continuous culture. In both populations, after an extensive number of generations had elapsed, clones were isolated in which the transposon Tn3 from the plasmid had integrated into the bacterial chromosome. In both cases examined, the transpositions were shown to increase relative fitness approximately 6-7%, in the environment in which the populations were maintained. The loci of integration were mapped to ~13.2 min (population 1) and ~32.8 min (population 2).
This article has been cited by other articles:
 |
|
 |
|
  A. Kalia, A. K. Mukhopadhyay, G. Dailide, Y. Ito, T. Azuma, B. C. Y. Wong, and D. E. Berg Evolutionary Dynamics of Insertion Sequences in Helicobacter pylori J. Bacteriol., November 15, 2004; 186(22): 7508 - 7520. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. J. Edwards and J. F. Y. Brookfield Transiently Beneficial Insertions Could Maintain Mobile DNA Sequences in Variable Environments Mol. Biol. Evol., January 1, 2003; 20(1): 30 - 37. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. van Belkum, M. Struelens, A. de Visser, H. Verbrugh, and M. Tibayrenc Role of Genomic Typing in Taxonomy, Evolutionary Genetics, and Microbial Epidemiology Clin. Microbiol. Rev., July 1, 2001; 14(3): 547 - 560. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Laurent, H. Lelievre, M. Cornu, F. Vandenesch, G. Carret, J. Etienne, and J.-P. Flandrois Fitness and competitive growth advantage of new gentamicin-susceptible MRSA clones spreading in French hospitals J. Antimicrob. Chemother., March 1, 2001; 47(3): 277 - 283. [Abstract] [Full Text] [PDF]
|
|