The Genetics of a Small Autosomal Region of Drosophila melanogaster Containing the Structural Gene for Alcohol Dehydrogenase. VII. Characterization of the Region Around the snail and cactus Loci

INVESTIGATIONS

The Genetics of a Small Autosomal Region of Drosophila melanogaster Containing the Structural Gene for Alcohol Dehydrogenase. VII. Characterization of the Region Around the snail and cactus Loci

M. Ashburner, P. Thompson, J. Roote, P. F. Lasko, Y. Grau, M. E. Messal, S. Roth and P. Simpson
Department of Genetics, University of Cambridge, Cambridge CB2 3EH, England

The genetic interval 35C to 36A on chromosome arm 2L of Drosophila melanogaster has been saturated for mutations with visible or lethal phenotypes. 38 loci have been characterized, including several maternal-effect lethals (vasa, Bic-C, chiffon, cactus and cornichon) and several early embryonic lethals, including snail and fizzy. About 130 deletions have been used to order these loci. Complex interactions between mutant alleles have been uncovered in the immediate genetic environs of the snail gene, as has further evidence for an interaction between this region and that including the nearby genes no-ocelli and elbow.

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