- THIS ARTICLE
- Full Text (PDF)
- Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Denniston, C.
- Articles by Crow, J. F.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Denniston, C.
- Articles by Crow, J. F.
Genetics, Vol 125, 201-205, Copyright © 1990
INVESTIGATIONS |
Alternative Fitness Models With the Same Allele Frequency Dynamics
C. Denniston and J. F. Crow
Laboratory of Genetics, University of Wisconsin, Madison, Wisconsin 53706
For any set of one- or two-locus genotypic fitnesses there are alternative sets, usually frequency-dependent and often with quite different biological meanings, that give rise to the same equations for change of allele or haplotype frequencies. Therefore, it is not possible to distinguish among alternative fitness models from allele or haplotype frequency trajectories or equilibrium distributions. For a single locus and for two loci when linkage equilibrium can be assumed, a simple procedure generates some of the alternative fitness sets.
This article has been cited by other articles:
 |
|
 |
|
  D. Meyer, R. M. Single, S. J. Mack, H. A. Erlich, and G. Thomson Signatures of Demographic History and Natural Selection in the Human Major Histocompatibility Complex Loci Genetics, August 1, 2006; 173(4): 2121 - 2142. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Williamson, A. Fledel-Alon, and C. D. Bustamante Population Genetics of Polymorphism and Divergence for Diploid Selection Models With Arbitrary Dominance Genetics, September 1, 2004; 168(1): 463 - 475. [Abstract] [Full Text] [PDF]
|
|