- THIS ARTICLE
- Full Text (PDF)
- Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Easteal, S.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Easteal, S.
Genetics, Vol 124, 165-173, Copyright © 1990
INVESTIGATIONS |
The Pattern of Mammalian Evolution and the Relative Rate of Molecular Evolution
S. Easteal
Human Genetics Group, John Curtin School of Medical Research, The Australian National University, Canberra ACT 2601, Australia
The rates of nucleotide substitution at four genes in four orders of eutherian mammals are compared in relative rate tests using marsupial orthologs for reference. There is no evidence of systematic variation in evolutionary rate among the orders. The sequences are used to reconstruct the phylogeny of the orders using maximum likelihood, parsimony and compatibility methods. A branching order of rodent then ungulate then primate and lagomorph is overwhelmingly indicated. The nodes of the nucleotide based cladograms are widely separated in relation to the total lengths of the branches. The assumption of a star phylogeny that underlies Kimura's test for molecular evolutionary rate variation is shown to be invalid for eutherian mammals. Excess variance in nucleotide or amino acid differences between mammalian orders, above that predicted by neutral theory is explained better by variation in divergence time than by variation in evolutionary rate.
This article has been cited by other articles:
 |
|
 |
|
  G. A. Huttley, M. J. Wakefield, and S. Easteal Rates of Genome Evolution and Branching Order from Whole Genome Analysis Mol. Biol. Evol., August 1, 2007; 24(8): 1722 - 1730. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. L. Rowe and R. L. Honeycutt Phylogenetic Relationships, Ecological Correlates, and Molecular Evolution Within the Cavioidea (Mammalia, Rodentia) Mol. Biol. Evol., March 1, 2002; 19(3): 263 - 277. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Eizirik, W. J. Murphy, and S. J. O'Brien Molecular Dating and Biogeography of the Early Placental Mammal Radiation J. Hered., March 1, 2001; 92(2): 212 - 219. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. W. Slade, C. Moritz, A. R. Hoelzel, and H. R. Burton Molecular Population Genetics of the Southern Elephant Seal Mirounga leonina Genetics, August 1, 1998; 149(4): 1945 - 1957. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Jimenez-Linan, B. S. Rubin, and J. C. King Examination of Guinea Pig Luteinizing Hormone-Releasing Hormone Gene Reveals a Unique Decapeptide and Existence of Two Transcripts in the Brain Endocrinology, October 1, 1997; 138(10): 4123 - 4130. [Abstract] [Full Text] [PDF]
|
|