- THIS ARTICLE
- Full Text (PDF)
- Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Woodard, C.
- Articles by Carlson, J.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Woodard, C.
- Articles by Carlson, J.
Genetics, Vol 123, 315-326, Copyright © 1989
INVESTIGATIONS |
Genetic Analysis of Olfactory Behavior in Drosophila: A New Screen Yields the ota Mutants
C. Woodard, T. Huang, H. Sun, S. L. Helfand and J. Carlson
Department of Biology, Yale University, New Haven, Connecticut 06511
A simple means of measuring Drosophila olfactory response is described, and the behavior which it measures is characterized. The assay was used to screen for X-linked mutants defective in olfactory function. Six ota mutants were isolated and characterized (ota = olfactory trap abnormal). Four of the mutants were found to be abnormal in another chemosensory behavior as well. Two of the mutant phenotypes extend to include another sensory system: they are defective in visual system physiology. All were normal, however, in a test of giant fiber system physiology. Two of the mutations are dominant, and the recessive mutations define two complementation groups. Mutations representing each complementation group, as well as one of the dominant mutations, were mapped. For the mutants with defective visual system physiology, the visual defects were shown to cosegregate with olfactory phenotypes.
This article has been cited by other articles:
 |
|
 |
|
  Y. Peng, J. E. Nielsen, J. P. Cunningham, and E. A. McGraw Wolbachia Infection Alters Olfactory-Cued Locomotion in Drosophila spp. Appl. Envir. Microbiol., July 1, 2008; 74(13): 3943 - 3948. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Keller and L. B. Vosshall Influence of odorant receptor repertoire on odor perception in humans and fruit flies PNAS, March 27, 2007; 104(13): 5614 - 5619. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. T. Diagana, U. Thomas, S. N. Prokopenko, B. Xiao, P. F. Worley, and J. B. Thomas Mutation of Drosophila homer Disrupts Control of Locomotor Activity and Behavioral Plasticity J. Neurosci., January 15, 2002; 22(2): 428 - 436. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M.-S. Kim and D. P. Smith The Invertebrate Odorant-binding Protein LUSH is required for Normal Olfactory Behavior in Drosophila Chem Senses, February 1, 2001; 26(2): 195 - 199. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. R.H. Anholt, J. J. Fanara, G. M. Fedorowicz, I. Ganguly, N. H. Kulkarni, T. F.C. Mackay, and S. M. Rollmann Functional Genomics of Odor-guided Behavior in Drosophila melanogaster Chem Senses, February 1, 2001; 26(2): 215 - 221. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. A. Osborne, J. S. de Belle, and M. B. Sokolowski Foraging Behaviour in Drosophila Larvae: Mushroom Body Ablation Chem Senses, February 1, 2001; 26(2): 223 - 230. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M.-S. Kim, A. Repp, and D. P. Smith LUSH Odorant-Binding Protein Mediates Chemosensory Responses to Alcohols in Drosophila melanogaster Genetics, October 1, 1998; 150(2): 711 - 721. [Abstract] [Full Text]
|
|
|
|
|
|
A. E. Dubin, M. M. Liles, and G. L. Harris The K+ Channel Gene Ether a Go-Go Is Required for the Transduction of a Subset of Odorants in Adult Drosophila melanogaster J. Neurosci., August 1, 1998; 18(15): 5603 - 5613. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. F. Eberl, G. M. Duyk, and N. Perrimon A genetic screen for mutations that disrupt an auditory response in Drosophila melanogaster PNAS, December 23, 1997; 94(26): 14837 - 14842. [Abstract] [Full Text] [PDF]
|
|