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Genetics, Vol 123, 249-253, Copyright © 1989
INVESTIGATIONS |
Interaction Between the sbcC Gene of Escherichia coli and the gam Gene of Phage {lambda}
S. K. Kulkarni and F. W. Stahl
Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403
gam mutants of phage {lambda} carrying long palindromes fail to form plaques on wild-type Escherichia coli but do grow on strains that are mutant in the sbcC gene. gam(+) {lambda} carrying the same palindrome grow on both hosts and on a host deleted for the recB, C and D genes. These results suggest that the Gam protein of {lambda}, known to interact also with E. coli's recBCD protein, can interact with the product of the sbcC gene.
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