- THIS ARTICLE
- Full Text (PDF)
- Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Sonti, R. V.
- Articles by Roth, J. R.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Sonti, R. V.
- Articles by Roth, J. R.
Genetics, Vol 123, 19-28, Copyright © 1989
INVESTIGATIONS |
Role of Gene Duplications in the Adaptation of Salmonella typhimurium to Growth on Limiting Carbon Sources
R. V. Sonti and J. R. Roth
To whom correspondence should be sent.
Duplication-containing cells are selected when growth of Salmonella typhimurium is limited by the availability of any one of several carbon and energy sources. Under conditions of extreme starvation, growth occurs almost exclusively in the duplication-containing fraction of the population. Cells with duplications of one large segment of the chromosome are repeatedly selected regardless of which of these carbon sources limits growth. The duplicated chromosomal segment encodes the transport systems for all of these carbon sources. This duplication is not selected during growth on a carbon source for which the permease is not included within the duplication segment. This suggests that the growth advantage conferred by the duplication may be due to increased transport of the limiting carbon source. Inclusion of the permease alone is not sufficient to explain the growth advantage of the duplications, since other common duplications that include the permease are not selected.
This article has been cited by other articles:
 |
|
 |
|
  U. Bergthorsson, D. I. Andersson, and J. R. Roth Ohno's dilemma: Evolution of new genes under continuous selection PNAS, October 23, 2007; 104(43): 17004 - 17009. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. I. Nilsson, A. Zorzet, A. Kanth, S. Dahlstrom, O. G. Berg, and D. I. Andersson Reducing the fitness cost of antibiotic resistance by amplification of initiator tRNA genes PNAS, May 2, 2006; 103(18): 6976 - 6981. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Porwollik, R. M.-Y. Wong, R. A. Helm, K. K. Edwards, M. Calcutt, A. Eisenstark, and M. McClelland DNA Amplification and Rearrangements in Archival Salmonella enterica Serovar Typhimurium LT2 Cultures J. Bacteriol., March 15, 2004; 186(6): 1678 - 1682. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Dvornyk, O. Vinogradova, and E. Nevo Origin and evolution of circadian clock genes in prokaryotes PNAS, March 4, 2003; 100(5): 2495 - 2500. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Gomez, M. Ladire, F. Marcille, and M. Fons Trypsin Mediates Growth Phase-Dependent Transcriptional Regulation of Genes Involved in Biosynthesis of Ruminococcin A, a Lantibiotic Produced by a Ruminococcus gnavus Strain from a Human Intestinal Microbiota J. Bacteriol., January 1, 2002; 184(1): 18 - 28. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. J. Wernegreen and N. A. Moran Vertical Transmission of Biosynthetic Plasmids in Aphid Endosymbionts (Buchnera) J. Bacteriol., January 15, 2001; 183(2): 785 - 790. [Abstract] [Full Text]
|
|
|
|
|
|
M. M. Riehle, A. F. Bennett, and A. D. Long Genetic architecture of thermal adaptation in Escherichia coli PNAS, January 5, 2001; (2001) 21448998. [Abstract] [Full Text]
|
|
|
|
|
|
R. Rajeshwari and R. V. Sonti Stationary-Phase Variation Due to Transposition of Novel Insertion Elements in Xanthomonas oryzae pv. oryzae J. Bacteriol., September 1, 2000; 182(17): 4797 - 4802. [Abstract] [Full Text]
|
|
|
|
|
|
B. E. Wright A Biochemical Mechanism for Nonrandom Mutations and Evolution J. Bacteriol., June 1, 2000; 182(11): 2993 - 3001. [Full Text]
|
|
|
|
|
|
E. R. Zinser and R. Kolter Mutations Enhancing Amino Acid Catabolism Confer a Growth Advantage in Stationary Phase J. Bacteriol., September 15, 1999; 181(18): 5800 - 5807. [Abstract] [Full Text]
|
|
|
|
|
|
C. H. Nakatsu, R. Korona, R. E. Lenski, F. J. de Bruijn, T. L. Marsh, and L. J. Forney Parallel and Divergent Genotypic Evolution in Experimental Populations of Ralstonia sp. J. Bacteriol., September 1, 1998; 180(17): 4325 - 4331. [Abstract] [Full Text]
|
|
|
|
|
|
R. Ravatn, S. Studer, D. Springael, A. J. B. Zehnder, and J. R. van der Meer Chromosomal Integration, Tandem Amplification, and Deamplification in Pseudomonas putida F1 of a 105-Kilobase Genetic Element Containing the Chlorocatechol Degradative Genes from Pseudomonas sp. Strain B13 J. Bacteriol., September 1, 1998; 180(17): 4360 - 4369. [Abstract] [Full Text]
|
|
|
|
|
|
M. M. Riehle, A. F. Bennett, and A. D. Long Genetic architecture of thermal adaptation in Escherichia coli PNAS, January 16, 2001; 98(2): 525 - 530. [Abstract] [Full Text] [PDF]
|
|