Genetics, Vol 121, 263-271, Copyright © 1989

INVESTIGATIONS

A Possible Case of Negative Segregation Distortion in the SD System of Drosophila melanogaster

Y. Hiraizumi
Department of Zoology, The University of Texas, Austin, Texas 78712

Models proposed to explain segregation distortion in Drosophila melanogaster are based partly upon the observation that, in the Sd heterozygous Rsp(i)/Rsp(s) male, the chromosome carrying the sensitive Rsp(s) allele is distorted, but the chromosome carrying the insensitive Rsp(i) allele is not. The results of the present study suggest that this may not always be the case. Under a certain genotypic condition, the chromosome carrying the Rsp(s) allele can be transmitted to the progeny in frequencies of more than 0.5 (about 0.6), or correspondingly, the chromosome carrying the Rsp(i) allele may be distorted with respect to the one with the Rsp(s) allele. Thus, the relative sensitivity and insensitivity of the two Rsp alleles in a male are not absolute, but relative; and they may be reversed depending upon the residual genotype. If this is true, a major modification of the current models or a proposal of an entirely new model may become necessary to explain the mechanism of segregation distortion satisfactorily.

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