Female Sterile Mutations on the Second Chromosome of Drosophila melanogaster. I. Maternal Effect Mutations

INVESTIGATIONS

Female Sterile Mutations on the Second Chromosome of Drosophila melanogaster. I. Maternal Effect Mutations

T. Schupbach and E. Wieschaus
Biology Department, Princeton University, Princeton, New Jersey 08544

In mutagenesis screens for recessive female sterile mutations on the second chromosome of Drosophila melanogaster 529 chromosomes were isolated which allow the homozygous females to survive, but cause them to be sterile. In 136 of these lines, mutant females produce morphologically normal eggs which cannot support normal embryonic development. These ``maternal-effect'' mutations fall into 67 complementation groups which define 23 multiply hit and 44 singly hit loci. In eggs from 14 complementation groups development is blocked before the formation of a syncytial blastoderm. In eggs from 12 complementation groups development is abnormal before cellularization, 17 complementation groups cause abnormal cellularization, 12 complementation groups cause changes in cellular morphology in early gastrulation stages, and 12 complementation groups seem to affect later embryonic development.

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Of flies and fishes
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[Abstract] [PDF]

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Genes & Dev., July 1, 1993; 7(7a): 1229 - 1243.
[Abstract] [PDF]

H J Doyle and J M Bishop
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Genes & Dev., April 1, 1993; 7(4): 633 - 646.
[Abstract] [PDF]

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Development, January 8, 1993; 118(4): 1245 - 1254.
[Abstract] [PDF]

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Homeostatic balance between dorsal and cactus proteins in the Drosophila embryo
Development, January 1, 1993; 117(1): 135 - 148.
[Abstract] [PDF]

C. F. Lehner
The pebble gene is required for cytokinesis in Drosophila
J. Cell Sci., December 1, 1992; 103(4): 1021 - 1030.
[Abstract] [PDF]

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The fat facets gene is required for Drosophila eye and embryo development
Development, December 1, 1992; 116(4): 985 - 1000.
[Abstract] [PDF]

D D Barker, C Wang, J Moore, L K Dickinson, and R Lehmann
Pumilio is essential for function but not for distribution of the Drosophila abdominal determinant Nanos.
Genes & Dev., December 1, 1992; 6(12a): 2312 - 2326.
[Abstract] [PDF]

L Segalat, R Perichon, J P Bouly, and J A Lepesant
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[Abstract] [PDF]

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Extracellular Morphogens in Drosophila Embryonic Dorsal-Ventral Patterning
Cold Spring Harb Symp Quant Biol, January 1, 1992; 57(0): 409 - 417.
[Abstract] [PDF]

D S Schneider, K L Hudson, T Y Lin, and K V Anderson
Dominant and recessive mutations define functional domains of Toll, a transmembrane protein required for dorsal-ventral polarity in the Drosophila embryo.
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[Abstract] [PDF]

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[Abstract] [PDF]

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Posterior localization of vasa protein correlates with, but is not sufficient for, pole cell development.
Genes & Dev., June 1, 1990; 4(6): 905 - 921.
[Abstract] [PDF]

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[Abstract] [PDF]

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Localized surface activity of torso, a receptor tyrosine kinase, specifies terminal body pattern in Drosophila.
Genes & Dev., December 1, 1989; 3(12b): 2025 - 2038.
[Abstract] [PDF]

H J Doyle, R Kraut, and M Levine
Spatial regulation of zerknullt: a dorsal-ventral patterning gene in Drosophila.
Genes & Dev., October 1, 1989; 3(10): 1518 - 1533.
[Abstract] [PDF]

L J Manseau and T Schupbach
cappuccino and spire: two unique maternal-effect loci required for both the anteroposterior and dorsoventral patterns of the Drosophila embryo.
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				J. K. Jang, T. Rahman, V. S. Kober, J. Cesario, and K. S. McKim Misregulation of the Kinesin-like Protein Subito Induces Meiotic Spindle Formation in the Absence of Chromosomes and Centrosomes Genetics, September 1, 2007; 177(1): 267 - 280. [Abstract] [Full Text] [PDF]

				H.-R. Chung, U. Lohr, and H. Jackle Lineage-specific expansion of the Zinc Finger Associated Domain ZAD Mol. Biol. Evol., September 1, 2007; 24(9): 1934 - 1943. [Abstract] [Full Text] [PDF]

				V. Barbosa, N. Kimm, and R. Lehmann A Maternal Screen for Genes Regulating Drosophila Oocyte Polarity Uncovers New Steps in Meiotic Progression Genetics, August 1, 2007; 176(4): 1967 - 1977. [Abstract] [Full Text] [PDF]

				K. Koizumi, H. Higashida, S. Yoo, M. S. Islam, A. I. Ivanov, V. Guo, P. Pozzi, S.-H. Yu, A. C. Rovescalli, D. Tang, et al. RNA interference screen to identify genes required for Drosophila embryonic nervous system development PNAS, March 27, 2007; 104(13): 5626 - 5631. [Abstract] [Full Text] [PDF]

				A. Swan and T. Schupbach The Cdc20 (Fzy)/Cdh1-related protein, Cort, cooperates with Fzy in cyclin destruction and anaphase progression in meiosis I and II in Drosophila Development, March 1, 2007; 134(5): 891 - 899. [Abstract] [Full Text] [PDF]

				J. M. Cesario, J. K. Jang, B. Redding, N. Shah, T. Rahman, and K. S. McKim Kinesin 6 family member Subito participates in mitotic spindle assembly and interacts with mitotic regulators J. Cell Sci., November 15, 2006; 119(22): 4770 - 4780. [Abstract] [Full Text] [PDF]

				S. J. Bultman, T. C. Gebuhr, H. Pan, P. Svoboda, R. M. Schultz, and T. Magnuson Maternal BRG1 regulates zygotic genome activation in the mouse. Genes & Dev., July 1, 2006; 20(13): 1744 - 1754. [Abstract] [Full Text] [PDF]

				J. K. Jang, T. Rahman, and K. S. McKim The Kinesinlike Protein Subito Contributes to Central Spindle Assembly and Organization of the Meiotic Spindle in Drosophila Oocytes Mol. Biol. Cell, October 1, 2005; 16(10): 4684 - 4694. [Abstract] [Full Text] [PDF]

				A. Swan, G. Barcelo, and T. Schupbach Drosophila Cks30A interacts with Cdk1 to target Cyclin A for destruction in the female germline Development, August 15, 2005; 132(16): 3669 - 3678. [Abstract] [Full Text] [PDF]

				M. G. Riparbelli and G. Callaini The meiotic spindle of the Drosophila oocyte: the role of Centrosomin and the central aster J. Cell Sci., July 1, 2005; 118(13): 2827 - 2836. [Abstract] [Full Text] [PDF]

				C. M. Field, M. Coughlin, S. Doberstein, T. Marty, and W. Sullivan Characterization of anillin mutants reveals essential roles in septin localization and plasma membrane integrity Development, June 15, 2005; 132(12): 2849 - 2860. [Abstract] [Full Text] [PDF]

				H. N. Skold, D. J. Komma, and S. A. Endow Assembly pathway of the anastral Drosophila oocyte meiosis I spindle J. Cell Sci., April 15, 2005; 118(8): 1745 - 1755. [Abstract] [Full Text] [PDF]

				J.-Y. Ji, J. Crest, and G. Schubiger Genetic interactions between Cdk1-CyclinB and the Separase complex in Drosophila Development, April 15, 2005; 132(8): 1875 - 1884. [Abstract] [Full Text] [PDF]

				S. Luschnig, B. Moussian, J. Krauss, I. Desjeux, J. Perkovic, and C. Nusslein-Volhard An F1 Genetic Screen for Maternal-Effect Mutations Affecting Embryonic Pattern Formation in Drosophila melanogaster Genetics, May 1, 2004; 167(1): 325 - 342. [Abstract] [Full Text] [PDF]

				J. H. Thomas and E. Wieschaus src64 and tec29 are required for microfilament contraction during Drosophila cellularization Development, February 15, 2004; 131(4): 863 - 871. [Abstract] [Full Text] [PDF]

				S. G. Martin, V. Leclerc, K. Smith-Litiere, and D. S. Johnston The identification of novel genes required for Drosophila anteroposterior axis formation in a germline clone screen using GFP-Staufen Development, September 1, 2003; 130(17): 4201 - 4215. [Abstract] [Full Text] [PDF]

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				W. Tadros, S. A. Houston, A. Bashirullah, R. L. Cooperstock, J. L. Semotok, B. H. Reed, and H. D. Lipshitz Regulation of Maternal Transcript Destabilization During Egg Activation in Drosophila Genetics, July 1, 2003; 164(3): 989 - 1001. [Abstract] [Full Text] [PDF]

				D. E. Koryakov, E. V. Domanitskaya, S. N. Belyakin, and I. F. Zhimulev Abnormal tissue-dependent polytenization of a block of chromosome 3 pericentric heterochromatin in Drosophila melanogaster J. Cell Sci., March 15, 2003; 116(6): 1035 - 1044. [Abstract] [Full Text] [PDF]

				K. Simin, A. Scuderi, J. Reamey, D. Dunn, R. Weiss, J. E. Metherall, and A. Letsou Profiling Patterned Transcripts in Drosophila Embryos Genome Res., July 1, 2002; 12(7): 1040 - 1047. [Abstract] [Full Text] [PDF]

				K. L. Giunta, J. K. Jang, E. A. Manheim, G. Subramanian, and K. S. McKim subito Encodes a Kinesin-like Protein Required for Meiotic Spindle Pole Formation in Drosophila melanogaster Genetics, April 1, 2002; 160(4): 1489 - 1501. [Abstract] [Full Text] [PDF]

				S. E. Mohr and R. E. Boswell Genetic Analysis of Drosophila melanogaster Polytene Chromosome Region 44D-45F: Loci Required for Viability and Fertility Genetics, April 1, 2002; 160(4): 1503 - 1510. [Abstract] [Full Text] [PDF]

				D. HWANG Modulation of the expression of cyclooxygenase-2 by fatty acids mediated through Toll-like receptor 4-derived signaling pathways FASEB J, December 1, 2001; 15(14): 2556 - 2564. [Abstract] [Full Text] [PDF]

				H. Butler, S. Levine, X. Wang, S. Bonyadi, G. Fu, P. Lasko, B. Suter, and R. Doerig Map Position and Expression of the Genes in the 38 Region of Drosophila Genetics, August 1, 2001; 158(4): 1597 - 1614. [Abstract] [Full Text] [PDF]

				L. Dobens, E Martin-Blanco, A Martinez-Arias, F. Kafatos, and L. Raftery Drosophila puckered regulates Fos/Jun levels during follicle cell morphogenesis Development, January 5, 2001; 128(10): 1845 - 1856. [Abstract] [PDF]

				K. Munn and R. Steward The shut-down Gene of Drosophila melanogaster Encodes a Novel FK506-Binding Protein Essential for the Formation of Germline Cysts During Oogenesis Genetics, September 1, 2000; 156(1): 245 - 256. [Abstract] [Full Text]