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Genetics, Vol 120, 605-613, Copyright © 1988
INVESTIGATIONS |
The Maintenance of Single-Locus Polymorphism. I. Numerical Studies of a Viability Selection Model
H. G. Spencer and R. W. Marks
Department of Biological Sciences, Stanford University, Stanford, California 94305, Museum of Comparative Zoology, Harvard University, Cambridge, Massachusetts 02138
The ability of viability selection to maintain single-locus polymorphism is investigated with two models in which the population is bombarded with a series of mutations with random fitnesses. In the first model, the population is allowed to reach equilibrium before mutation resumes; in the second the iterations and mutation occur simultaneously. Monte Carlo simulations of these models show that viability selection is easily able to maintain stable 6- or 7-allele polymorphisms and that monomorphisms and diallelic polymorphisms are uncommon. The question of how monomorphisms arise is also discussed.
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