Genetics, Vol 120, 495-502, Copyright © 1988


INVESTIGATIONS

Studies of the Genetic Organization of the vestigial Microregion of Drosophila melanogaster

P. F. Lasko and M. L. Pardue
Present address: Department of Genetics, University of Cambridge, Downing Street, Cambridge, England CB2 3EH.

The region of the second chromosome of Drosophila melanogaster defined by Df(2R)vgB was screened for recessive lethal and visible mutations. Fifty-eight new recessive alleles fall into 17 complementation groups. Many new vg alleles were also isolated in a screen for new vg deficiencies. The breakpoints of the new vg deficiencies were nonrandomly distributed. The distal breakpoints of twelve of 20 deficiencies overlapping Df(2R)vgB are genetically identical to that of Df(2R)vgD, coinciding with the position of a complex, pleiotropic locus, l(2)49Ea-Psc-Su(z)2.


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