- THIS ARTICLE
- Full Text (PDF)
- Alert me when this article is cited
- Alert me if a correction is posted
- SERVICES
- Similar articles in this journal
- Similar articles in PubMed
- Alert me to new issues of the journal
- Download to citation manager
- Reprints & Permissions
- CITING ARTICLES
- Citing Articles via HighWire
- Citing Articles via Google Scholar
- GOOGLE SCHOLAR
- Articles by Clark, A. G.
- Search for Related Content
- PUBMED
- PubMed Citation
- Articles by Clark, A. G.
NATURAL SELECTION WITH NUCLEAR AND CYTOPLASMIC TRANSMISSION. II. TESTS WITH DROSOPHILA FROM DIVERSE POPULATIONS
Andrew G. Clark 1
1 Department of Biology, Pennsylvania State University, University
Park, Pennsylvania 16802
Observations of intraspecific variation in organelle DNA have prompted a renewed interest in the evolutionary consequences of cytoplasmically transmitted factors. Attempts to quantify the significance of cytoplasmic effects are frequently limited by the difficulty in partitioning the cause of reciprocal cross differences among a series of possibilities. In the experiment reported here the nuclear genomes of a set of six lines of Drosophila melanogaster from diverse geographic locations were replaced in a series of cytoplasms. The segregation of the SM5 balancer chromsome was scored in a factorial design, and the data allowed a partitioning of variance such that cytoplasmic effects were distinguished from maternal effects and meiotic drive. An attempt was made to avoid the confounding problem of hybrid dysgenesis by performing the entire experiment (including chromosomal extractions) in a P cytotype. Results indicated a significant contribution of cytoplasm to the variance in SM5 segregation. Error variance showed an increasing trend as the experiment proceeded, and additional tests indicated that this was due to an accumulation of chromosomal mutations. These findings are interpreted in light of the population genetic theory that addresses the maintenance of cytoplasmic polymorphism.
Submitted on December 17, 1984Accepted on May 20, 1985
This article has been cited by other articles:
 |
|
 |
|
  D. K. Dowling, U. Friberg, F. Hailer, and G. Arnqvist Intergenomic Epistasis for Fitness: Within-Population Interactions Between Cytoplasmic and Nuclear Genes in Drosophila melanogaster Genetics, January 1, 2007; 175(1): 235 - 244. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M. Rand, A. G. Clark, and L. M. Kann Sexually Antagonistic Cytonuclear Fitness Interactions in Drosophila melanogaster Genetics, September 1, 2001; 159(1): 173 - 187. [Abstract] [Full Text] [PDF]
|
|