COUPLED INSTABILITY OF TWO X-LINKED GENES IN DROSOPHILA MAURITIANA: GERMINAL AND SOMATIC MUTABILITY

James W. Jacobson 1 and Daniel L. Hartl 1

1 Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110-1095

A highly unstable allele has been isolated at the white locus of Drosophila mauritiana, a sibling species of D. melanogaster . This allele, white-peach (wpch), mutates spontaneously in males and females to give both wild-type and bleached-white derivatives. The mutation frequency is about 10-3 mutations/generation. There is no evidence for clustering among mutant progeny, and phenotypically wpch flies with mosaic patches of wild-type tissue in the eyes are frequently recovered. Another X-linked locus, plum, is destabilized when wpch is on the same X chromosome.

Submitted on January 7, 1985
Accepted on May 13, 1985




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