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MOLECULAR MAPPING OF A GENE CLUSTER FLANKING THE DROSOPHILA DOPA DECARBOXYLASE GENE
Denise Gilbert 1, Jay Hirsh 2, and T. R. F. Wright 3
1 Department of Biological Chemistry and Committee on Cell and
Developmental Biology, Harvard Medical School, Boston, Massachusetts 02115
2 Department of Biological Chemistry, Harvard Medical School,
Boston, Massachusetts 02115
3 Department of Biology, University of Virginia, Charlottesville,
Virginia 22901
Nine lethal complementation groups flanking the Drosophila Dopa decarboxylase (Ddc) gene, have been localized within 100 kb of cloned chromosomal DNA. Six of these complementation groups are within 23 kb of DNA, and all ten complementation groups, including Ddc, lie within 78-82 kb of DNA. The potential significance of this unusually high gene density is discussed.
Submitted on November 17, 1983Accepted on January 3, 1984
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