A CYTOGENETIC ANALYSIS OF THE CHROMOSOMAL REGION SURROUNDING THE alpha-GLYCEROPHOSPHATE DEHYDROGENASE LOCUS OF DROSOPHILA MELANOGASTER

1 Section of Genetics and Development, Cornell University, Ithaca, New York 14853

The chromosomal region surrounding the structural gene for alpha-glycerophosphate dehydrogenase (alphaGpdh, 2-20.5) of Drosophila melanogaster has been studied in detail. Forty-three EMS-induced recessive lethal mutations and five previously identified visible mutations have been localized within the 25A-27D region of chromosome 2 by deficiency mapping and in some cases by a recombination analysis. The 43 lethal mutations specify 17 lethal loci. alphaGpdh has been localized to a single polytene chromosome band, 25F5, and there apparently are no lethals that map to the alphaGpdh locus.

Submitted on April 12, 1982
Accepted on June 9, 1983




This article has been cited by other articles:


Home page
Mol. Biol. CellHome page
K. Patterson, A. B. Molofsky, C. Robinson, S. Acosta, C. Cater, and J. A. Fischer
The Functions of Klarsicht and Nuclear Lamin in Developmentally Regulated Nuclear Migrations of Photoreceptor Cells in the Drosophila Eye
Mol. Biol. Cell, February 1, 2004; 15(2): 600 - 610.
[Abstract] [Full Text] [PDF]