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A CYTOGENETIC ANALYSIS OF THE CHROMOSOMAL REGION SURROUNDING
THE
-GLYCEROPHOSPHATE DEHYDROGENASE LOCUS OF DROSOPHILA MELANOGASTER
Michael A. Kotarski 1, Sally Pickert 1, and Ross J. MacIntyre 1
1 Section of Genetics and Development, Cornell University, Ithaca,
New York 14853
The chromosomal region surrounding the structural gene for
-glycerophosphate
dehydrogenase (
Gpdh, 2-20.5) of Drosophila melanogaster
has been studied in detail. Forty-three EMS-induced recessive lethal
mutations and five previously identified visible mutations have been localized
within the 25A-27D region of chromosome 2 by deficiency mapping and
in some cases by a recombination analysis. The 43 lethal mutations specify
17 lethal loci.
Gpdh has been localized to a single polytene
chromosome band, 25F5, and there apparently are no lethals that map to the
Gpdh locus.
Accepted on June 9, 1983
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