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NEW SUPPRESSORS OF FRAMESHIFT MUTATIONS IN SALMONELLA TYPHIMURIUM
Tadahiko Kohno 1, Lionello Bossi 1, and John R. Roth 1
1 Department of Biology, University of Utah, Salt Lake City,
Utah 84112
Several new types of suppressor mutants have been isolated. These were identified among revertants of mutants originally generated by mutagens other than the acridine-derived ICR191. The new suppressors correct mutations other than those with runs of C or G which are recognized by the previously described suppressors. Several frameshift mutations are corrected by more than one suppressor type. Apparently, the DNA base sequence near these mutant sites includes sites of action for several distinct suppressor types.
Submitted on February 24, 1982Accepted on September 4, 1982
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