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FREQUENCY OF
-RAY INDUCED SPECIFIC LOCUS AND RECESSIVE
LETHAL MUTATIONS IN MATURE GERM CELLS OF THE ZEBRAFISH, BRACHYDANIO RERIO
Sankar Chakrabarti 1, George Streisinger 1, Fred Singer 1, and Charline Walker 1
1 Institute of Molecular Biology, University of Oregon, Eugene,
Oregon 97403
Specific locus and recessive lethal mutations are induced by
-rays
with approximately first order kinetics in the zebrafish (Brachydanio
rerio) with frequencies of 4 x 10-5 r-1
and 4 x 10-3 r-1, respectively.
The surprisingly low ratio (100:1) of recessive lethals to specific locus
mutations may be due to the induction of large deficiencies by
-rays.
Accepted on September 27, 1982
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