Investigations

• Methods, Technology, and Resources

  • Efficient Generation of Endogenous Fluorescent Reporters by Nested CRISPR in Caenorhabditis elegans

    Jeremy Vicencio, Carmen Martínez-Fernández, Xènia Serrat, Julián Cerón
  • Twenty-Seven Tamoxifen-Inducible iCre-Driver Mouse Strains for Eye and Brain, Including Seventeen Carrying a New Inducible-First Constitutive-Ready Allele

    Open Access

    Andrea J. Korecki, Jack W. Hickmott, Siu Ling Lam, Lisa Dreolini, Anthony Mathelier, Oliver Baker, Claudia Kuehne, Russell J. Bonaguro, Jillian Smith, Chin-Vern Tan, Michelle Zhou, Daniel Goldowitz, Jan M. Deussing, A. Francis Stewart, Wyeth W. Wasserman, Robert A. Holt, Elizabeth M. Simpson

• Statistical Genetics and Genomics

  • Adjusting for Principal Components of Molecular Phenotypes Induces Replicating False Positives

    Andy Dahl, Vincent Guillemot, Joel Mefford, Hugues Aschard, Noah Zaitlen
  • Fast Estimation of Recombination Rates Using Topological Data Analysis

    Devon P. Humphreys, Melissa R. McGuirl, Michael Miyagi, Andrew J. Blumberg

• Gene Expression

  • Sequence Characteristics Distinguish Transcribed Enhancers from Promoters and Predict Their Breadth of Activity

    Laura L. Colbran, Ling Chen, John A. Capra
  • Modulation of Gene Silencing by Cdc7p via H4 K16 Acetylation and Phosphorylation of Chromatin Assembly Factor CAF-1 in Saccharomyces cerevisiae

    Tiffany J. Young, Yi Cui, Joseph Irudayaraj, Ann L. Kirchmaier
  • Evolutionary Loss of Genomic Proximity to Conserved Noncoding Elements Impacted the Gene Expression Dynamics During Mammalian Brain Development

    Meenakshi Bagadia, Keerthivasan Raanin Chandradoss, Yachna Jain, Harpreet Singh, Mohan Lal, Kuljeet Singh Sandhu

• Cellular Genetics

  • Integration of Self and Non-self Recognition Modulates Asexual Cell-to-Cell Communication in Neurospora crassa

    Monika S. Fischer, Wilfried Jonkers, N. Louise Glass
  • Distribution of Proteins at the Inner Nuclear Membrane Is Regulated by the Asi1 E3 Ligase in Saccharomyces cerevisiae

    Open Access

    Christine J. Smoyer, Sarah E. Smith, Jennifer M. Gardner, Scott McCroskey, Jay R. Unruh, Sue L. Jaspersen
  • A Receptor Tyrosine Kinase Network Regulates Neuromuscular Function in Response to Oxidative Stress in Caenorhabditis elegans

    Sungjin Kim, Derek Sieburth

• Developmental and Behavioral Genetics

  • Purine Homeostasis Is Necessary for Developmental Timing, Germline Maintenance and Muscle Integrity in Caenorhabditis elegans

    Roxane Marsac, Benoît Pinson, Christelle Saint-Marc, María Olmedo, Marta Artal-Sanz, Bertrand Daignan-Fornier, José-Eduardo Gomes
  • Necessity and Contingency in Developmental Genetic Screens: EGF, Wnt, and Semaphorin Pathways in Vulval Induction of the Nematode Oscheius tipulae

    Open Access

    Amhed M. Vargas-Velazquez, Fabrice Besnard, Marie-Anne Félix
  • Multiple Pathways Act Together To Establish Asymmetry of the Ventral Nerve Cord in Caenorhabditis elegans

    Jesse Taylor, Harald Hutter

• Population and Evolutionary Genetics

  • A Shift in Aggregation Avoidance Strategy Marks a Long-Term Direction to Protein Evolution

    Scott G. Foy, Benjamin A. Wilson, Jason Bertram, Matthew H. J. Cordes, Joanna Masel
  • Interference Effects of Deleterious and Beneficial Mutations in Large Asexual Populations

    Kavita Jain
  • The Effects of Demography and Genetics on the Neutral Distribution of Quantitative Traits

    Evan M. Koch

• Genetics of Complex Traits

  • Modeling Heterogeneity in the Genetic Architecture of Ethnically Diverse Groups Using Random Effect Interaction Models

    Open Access

    Yogasudha Veturi, Gustavo de los Campos, Nengjun Yi, Wen Huang, Ana I. Vazquez, Brigitte Kühnel
  • Long-Term Population Studies Uncover the Genome Structure and Genetic Basis of Xenobiotic and Host Plant Adaptation in the Herbivore Tetranychus urticae

    Nicky Wybouw, Olivia Kosterlitz, Andre H. Kurlovs, Sabina Bajda, Robert Greenhalgh, Simon Snoeck, Huyen Bui, Astrid Bryon, Wannes Dermauw, Thomas Van Leeuwen, Richard M. Clark
  • A Multivariate Genome-Wide Association Study of Wing Shape in Drosophila melanogaster

    William Pitchers, Jessica Nye, Eladio J. Márquez, Alycia Kowalski, Ian Dworkin, David Houle
  • Dissection of Complex, Fitness-Related Traits in Multiple Drosophila Mapping Populations Offers Insight into the Genetic Control of Stress Resistance

    Open Access

    Elizabeth R. Everman, Casey L. McNeil, Jennifer L. Hackett, Clint L. Bain, Stuart J. Macdonald
  • Layers of Cryptic Genetic Variation Underlie a Yeast Complex Trait

    Open Access

    Jonathan T. Lee, Alessandro L. V. Coradini, Amy Shen, Ian M. Ehrenreich